Literature DB >> 18342174

Functional and morphological effects of postpercutaneous nephrolithotomy superselective renal angiographic embolization.

Ahmed R el-Nahas1, Ahmed A Shokeir, Tarek Mohsen, Hossam Gad, Ahmed M el-Assmy, Tarek el-Diasty, Hamdy A el-Kappany.   

Abstract

OBJECTIVES: To evaluate the functional and morphological effects of postpercutaneous nephrolithotomy (PCNL) superselective renal angiographic embolization.
METHODS: Between January 1995 and March 2006, superselective renal angiography was needed to control severe bleeding after 41 of 4095 PCNL procedures (1%). We evaluated the short-term effects of embolization after 3 months with renal ultrasonography (RUS), dimercaptosuccinic acid (DMSA) renal scan, and estimation of serum creatinine. We evaluated long-term morphological and functional effects with RUS, DMSA renal scan, and excretory urography (IVU).
RESULTS: Bleeding was controllable with superselective embolization in 38 patients (93%). Six of them developed early postembolization complications, in the form of perinephric hematoma in 4 and urinary leakage in 2 patients. At 3 months, serum creatinine levels increased in 3 of 9 patients with a solitary kidney, but none required renal replacement therapy. Long-term follow-up was completed for 30 patients for a mean period of 3.9 +/- 2.3 years. We performed IVU for 27 patients. Among them, 2 renal units (7%) showed no dye excretion. DMSA scans showed homogeneous distribution of radiotracer with no evidence of photopenic areas in 6 renal units (20%). The mean percentage of DMSA uptake by the corresponding kidney improved from 25 +/- 9% at the 3-month scans to 34 +/- 11% at the last follow-up scans (P <0.001).
CONCLUSIONS: The short-term deleterious effects of superselective renal embolization for post-PCNL renal vascular injuries were more pronounced in patients with a solitary kidney. However, the long-term follow-up showed functional and morphological improvements.

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Year:  2008        PMID: 18342174     DOI: 10.1016/j.urology.2007.10.033

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


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