Hélio Plapler1. 1. Department of Surgery, Universidade Federal de São Paulo, São Paulo, Brazil. helio@plapler.com.br
Abstract
OBJECTIVE: Detailed here is an experimental model in monkeys of a new approach to treat hemorrhoids using a diode laser. BACKGROUND DATA: Hemorrhoids are a common source of pain and suffering. Endovascular laser therapy for variceal veins is a method that potentially could be used in the treatment of hemorrhoids. There is currently no such method described in the literature. MATERIALS AND METHODS: Hemorrhoids were induced in monkeys by ligation of the inferior hemorrhoidal vein, similar to their cause in humans. After the piles were identified, laser fibers were introduced into them, and they were irradiated with laser energy (810 nm at 1-2 W in 1-sec pulses of 1-2 J each, for a total fluency of 4-10 J). RESULTS: The piles were completely reduced, and histological examination performed 10 d post-surgery showed reduction of the dilated vessels and complete healing. The laser energy was not delivered directly into the veins, but instead to the surrounding submucosal interstitial tissue, effectively reducing the hemorrhoids. CONCLUSION: The diode laser energy delivered into the hemorrhoids led to their complete resolution. Further clinical trials using this protocol must be carried out to determine its applicability to human hemorrhoids.
OBJECTIVE: Detailed here is an experimental model in monkeys of a new approach to treat hemorrhoids using a diode laser. BACKGROUND DATA: Hemorrhoids are a common source of pain and suffering. Endovascular laser therapy for variceal veins is a method that potentially could be used in the treatment of hemorrhoids. There is currently no such method described in the literature. MATERIALS AND METHODS:Hemorrhoids were induced in monkeys by ligation of the inferior hemorrhoidal vein, similar to their cause in humans. After the piles were identified, laser fibers were introduced into them, and they were irradiated with laser energy (810 nm at 1-2 W in 1-sec pulses of 1-2 J each, for a total fluency of 4-10 J). RESULTS: The piles were completely reduced, and histological examination performed 10 d post-surgery showed reduction of the dilated vessels and complete healing. The laser energy was not delivered directly into the veins, but instead to the surrounding submucosal interstitial tissue, effectively reducing the hemorrhoids. CONCLUSION: The diode laser energy delivered into the hemorrhoids led to their complete resolution. Further clinical trials using this protocol must be carried out to determine its applicability to humanhemorrhoids.
Authors: Donatas Danys; Julius Pacevicius; Gabija Makunaite; Rolandas Palubeckas; Antanas Mainelis; Narimantas Markevicius; Kestutis Strupas; Tomas Poskus Journal: Open Med (Wars) Date: 2020-03-08