| Literature DB >> 18338913 |
Sophie Laurent1, Luce Vander Elst, Coralie Thirifays, Robert N Muller.
Abstract
Proton relaxometric properties of unilamellar DPPC liposomes embedding an amphiphilic paramagnetic chelate (Gd-DTPA-BC(14)A) in both layers of the phospholipid membrane or only in the external one are compared. The results show that the membrane's water permeability is able to quench the effect of the paramagnetic complexes located in the internal layer of DPPC liposomes, leading thus to an apparent lower global relaxivity.Entities:
Mesh:
Substances:
Year: 2008 PMID: 18338913 DOI: 10.1021/la800148a
Source DB: PubMed Journal: Langmuir ISSN: 0743-7463 Impact factor: 3.882