Literature DB >> 18338913

Paramagnetic liposomes: inner versus outer membrane relaxivity of DPPC liposomes incorporating lipophilic gadolinium complexes.

Sophie Laurent1, Luce Vander Elst, Coralie Thirifays, Robert N Muller.   

Abstract

Proton relaxometric properties of unilamellar DPPC liposomes embedding an amphiphilic paramagnetic chelate (Gd-DTPA-BC(14)A) in both layers of the phospholipid membrane or only in the external one are compared. The results show that the membrane's water permeability is able to quench the effect of the paramagnetic complexes located in the internal layer of DPPC liposomes, leading thus to an apparent lower global relaxivity.

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Year:  2008        PMID: 18338913     DOI: 10.1021/la800148a

Source DB:  PubMed          Journal:  Langmuir        ISSN: 0743-7463            Impact factor:   3.882


  6 in total

Review 1.  Vascular targeting of nanoparticles for molecular imaging of diseased endothelium.

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2.  Formulation and characterisation of magnetic resonance imageable thermally sensitive liposomes for use with magnetic resonance-guided high intensity focused ultrasound.

Authors:  Ayele H Negussie; Pavel S Yarmolenko; Ari Partanen; Ashish Ranjan; Genevieve Jacobs; David Woods; Henry Bryant; David Thomasson; Mark W Dewhirst; Bradford J Wood; Matthew R Dreher
Journal:  Int J Hyperthermia       Date:  2011       Impact factor: 3.914

Review 3.  Targeted nanotechnology for cancer imaging.

Authors:  Randall Toy; Lisa Bauer; Christopher Hoimes; Ketan B Ghaghada; Efstathios Karathanasis
Journal:  Adv Drug Deliv Rev       Date:  2014-08-09       Impact factor: 15.470

Review 4.  Engineering Gd-loaded nanoparticles to enhance MRI sensitivity via T(1) shortening.

Authors:  Michael A Bruckman; Xin Yu; Nicole F Steinmetz
Journal:  Nanotechnology       Date:  2013-10-24       Impact factor: 3.874

5.  Liposomal Fe(III) Macrocyclic Complexes with Hydroxypropyl Pendants as MRI Probes.

Authors:  Samira M Abozeid; Md Saiful I Chowdhury; Didar Asik; Joseph A Spernyak; Janet R Morrow
Journal:  ACS Appl Bio Mater       Date:  2021-10-15

6.  Relaxivities of paramagnetic liposomes: on the importance of the chain type and the length of the amphiphilic complex.

Authors:  Sophie Laurent; Luce Vander Elst; Coralie Thirifays; Robert N Muller
Journal:  Eur Biophys J       Date:  2008-04-22       Impact factor: 1.733

  6 in total

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