Literature DB >> 18338779

Comprehensive pouch clinic concept for follow-up of patients after ileal pouch anal anastomosis: report of 3 years' experience in a tertiary referral center.

Hagit Tulchinsky1, Iris Dotan, Arik Alper, Eli Brazowski, Joseph M Klausner, Zamir Halpern, Micha Rabau.   

Abstract

BACKGROUND: We designed and evaluated a novel concept in enhancing postoperative care of patients following restorative proctocolectomy (RPC) for ulcerative colitis (UC) and determined the risk factors, incidence, and nature of RPC-associated complications in this population.
METHODS: The study cohort consisted of consecutive UC patients post-RPC attending a comprehensive pouch clinic run by a gastroenterologist and a colorectal surgeon in a tertiary care medical center (from January 2003 to December 2005). Data were collected on their medical history, physical examination, laboratory tests, pouch endoscopy and biopsies, and anonymous in-house patient satisfaction questionnaires mailed to the first 90 patients. Assessment was also done on data regarding risk factors, incidence, and nature of RPC-associated complications.
RESULTS: A total of 120 UC patients with a functioning pouch visited the clinic: mean age 37 years, range 13-75; 57 males; mean disease duration 11 years; mean follow-up 65 months. Of the 55 patients who responded to the questionnaire, 48 (87%) felt that the comprehensive clinic significantly improved the quality of their care. The major complications were pouchitis (52%), extraintestinal manifestations, pouch-related fistula, and mechanical dysfunction. The risk factors for the development of pouchitis were time since surgery, >1-stage surgery, and reason for surgery (acute exacerbation/intractable disease more than dysplasia/cancer); the latter was the only independent risk factor.
CONCLUSIONS: The pouch clinic concept significantly enhanced patient satisfaction. The most common RPC-associated complication was pouchitis. Risk factors for developing pouchitis were duration since operation, >1-stage operation, and indication for surgery.

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Year:  2008        PMID: 18338779     DOI: 10.1002/ibd.20430

Source DB:  PubMed          Journal:  Inflamm Bowel Dis        ISSN: 1078-0998            Impact factor:   5.325


  9 in total

1.  Multidisciplinary Team-Based Approaches to IBD Management: How Might "One-Stop Shopping" Work for Complex IBD Care?

Authors:  Chang Kyun Lee; Gil Y Melmed
Journal:  Am J Gastroenterol       Date:  2017-05-16       Impact factor: 10.864

Review 2.  Novel Indications for Fecal Microbial Transplantation: Update and Review of the Literature.

Authors:  Nathaniel Aviv Cohen; Nitsan Maharshak
Journal:  Dig Dis Sci       Date:  2017-03-17       Impact factor: 3.199

Review 3.  British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults.

Authors:  Christopher Andrew Lamb; Nicholas A Kennedy; Tim Raine; Philip Anthony Hendy; Philip J Smith; Jimmy K Limdi; Bu'Hussain Hayee; Miranda C E Lomer; Gareth C Parkes; Christian Selinger; Kevin J Barrett; R Justin Davies; Cathy Bennett; Stuart Gittens; Malcolm G Dunlop; Omar Faiz; Aileen Fraser; Vikki Garrick; Paul D Johnston; Miles Parkes; Jeremy Sanderson; Helen Terry; Daniel R Gaya; Tariq H Iqbal; Stuart A Taylor; Melissa Smith; Matthew Brookes; Richard Hansen; A Barney Hawthorne
Journal:  Gut       Date:  2019-09-27       Impact factor: 23.059

4.  Diet of patients after pouch surgery may affect pouch inflammation.

Authors:  Orit Ianco; Hagit Tulchinsky; Michal Lusthaus; Amos Ofer; Erwin Santo; Nachum Vaisman; Iris Dotan
Journal:  World J Gastroenterol       Date:  2013-10-14       Impact factor: 5.742

5.  Adherence to the Mediterranean diet is associated with decreased fecal calprotectin in patients with ulcerative colitis after pouch surgery.

Authors:  L Godny; L Reshef; T Pfeffer-Gik; I Goren; H Yanai; H Tulchinsky; U Gophna; I Dotan
Journal:  Eur J Nutr       Date:  2019-12-07       Impact factor: 5.614

Review 6.  Update of complications and functional outcome of the ileo-pouch anal anastomosis: overview of evidence and meta-analysis of 96 observational studies.

Authors:  Sharonne de Zeeuw; Usama Ahmed Ali; Usama Ahmed Ali; Rogier A R T Donders; Willem E Hueting; Frederik Keus; Cees J H M van Laarhoven
Journal:  Int J Colorectal Dis       Date:  2012-01-10       Impact factor: 2.571

Review 7.  Optimising the Inflammatory Bowel Disease Unit to Improve Quality of Care: Expert Recommendations.

Authors:  Edouard Louis; Iris Dotan; Subrata Ghosh; Liat Mlynarsky; Catherine Reenaers; Stefan Schreiber
Journal:  J Crohns Colitis       Date:  2015-05-18       Impact factor: 9.071

8.  MicroRNAs Expression in the Ileal Pouch of Patients with Ulcerative Colitis Is Robustly Up-Regulated and Correlates with Disease Phenotypes.

Authors:  Shay Ben-Shachar; Henit Yanai; Hadas Sherman Horev; Hofit Elad; Liran Baram; Ofer Issakov; Hagit Tulchinsky; Metsada Pasmanik-Chor; Noam Shomron; Iris Dotan
Journal:  PLoS One       Date:  2016-08-18       Impact factor: 3.240

9.  Clinical approach to skin eruptions induced by anti-TNF agents among patients with inflammatory bowel diseases: insights from a multidisciplinary IBD-DERMA clinic.

Authors:  Henit Yanai; Hadar Amir Barak; Jacob E Ollech; Irit Avni Biron; Idan Goren; Yifat Snir; Hagar Banai Eran; Yelena Broitman; Maya Aharoni Golan; Elena Didkovsky; Iris Amitay-Laish; Ayelet Ollech; Emmilia Hodak; Iris Dotan; Lev Pavlovsky
Journal:  Therap Adv Gastroenterol       Date:  2021-11-08       Impact factor: 4.409

  9 in total

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