Literature DB >> 18338743

Use of a topical emulsion for wound healing.

Joel L Cohen1, Joseph L Jorizzo, Leon H Kircik.   

Abstract

Treatment of skin trauma following removal of actinic keratoses and skin cancer lesions and following radiation therapy for breast cancer is an often under-treated problem compared to the primary condition. However, skin trauma can cause patients significant discomfort, pain, and loss of quality of life. Palliative treatments such as lotions and ointments may help soothe the skin trauma, but helping the healing process is the best way to treat the wound and relieve patients of their discomfort. In clinical trials, the use of Biafine, a topical emulsion, promoted wound healing following these clinical situations by increasing the number of macrophages recruited to a wound and thus enhancing healing. This topical emulsion has also been proven to be soothing for the patient. This review will discuss the molecular mechanisms of wound healing and the uses of Biafine in the treatment of skin damage caused by procedures for various conditions such as actinic keratosis, skin cancer lesions, and radiation dermatitis.

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Year:  2007        PMID: 18338743

Source DB:  PubMed          Journal:  J Support Oncol        ISSN: 1544-6794


  2 in total

1.  Repeated measures analyses of dermatitis symptom evolution in breast cancer patients receiving radiotherapy in a phase 3 randomized trial of mometasone furoate vs placebo (N06C4 [alliance]).

Authors:  Terence T Sio; Pamela J Atherton; Brandon J Birckhead; David J Schwartz; Jeff A Sloan; Drew K Seisler; James A Martenson; Charles L Loprinzi; Patricia C Griffin; Roscoe F Morton; Jon C Anders; Thomas J Stoffel; Robert E Haselow; Rex B Mowat; Michelle A Neben Wittich; James D Bearden; Robert C Miller
Journal:  Support Care Cancer       Date:  2016-04-14       Impact factor: 3.603

2.  The effect of Quercus brantii gall extract on burn wound healing in rat.

Authors:  Faraidoon Haghdoost; Mohammad Mehdi Baradaran Mahdavi; Behzad Zolfaghari; Mohammad Hossein Sanei; Somaye Najafi; Alireza Zandifar; Navid Manouchehri; Shaghayegh Haghjooy Javanmard
Journal:  Iran J Basic Med Sci       Date:  2016-10       Impact factor: 2.699

  2 in total

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