Literature DB >> 18338046

Chiral amine-thioureas bearing multiple hydrogen bonding donors: highly efficient organocatalysts for asymmetric Michael addition of acetylacetone to nitroolefins.

Chun-Jiang Wang1, Zhi-Hai Zhang, Xiu-Qin Dong, Xiao-Jun Wu.   

Abstract

New bifunctional organocatalysts amine-thioureas bearing multiple hydrogen bonding donors were synthesized and applied in catalytic asymmetric Michael addition of acetylacetone to aryl and alkyl nitroolefins. Multiple hydrogen bonding donors play a significant role in accelerating reactions, improving yields and enantioselectivities.

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Year:  2008        PMID： 18338046     DOI： 10.1039/b718949d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Formal [4 + 2] cycloaddition of imines with alkoxyisocoumarins.

Authors:  Claire L Jarvis; Neyra M Jemal; Spencer Knapp; Daniel Seidel
Journal:  Org Biomol Chem       Date:  2018-06-13       Impact factor: 3.876

2.  Novel ionic liquid with both Lewis and Brønsted acid sites for Michael addition.

Authors:  Xiaoyue Jiang; Weidong Ye; Xiaohua Song; Wenxin Ma; Xuejun Lao; Runpu Shen
Journal:  Int J Mol Sci       Date:  2011-10-28       Impact factor: 5.923

3.  Organocatalytic Michael addition of 1,3-dicarbonyl indane compounds to nitrostyrenes.

Authors:  Zhen-Yu Jiang; Hua-Meng Yang; Ya-Dong Ju; Li Li; Meng-Xian Luo; Guo-Qiao Lai; Jian-Xiong Jiang; Li-Wen Xu
Journal:  Molecules       Date:  2010-04-12       Impact factor: 4.411

4.  Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes.

Authors:  Zubeda Begum; Haruka Sannabe; Chigusa Seki; Yuko Okuyama; Eunsang Kwon; Koji Uwai; Michio Tokiwa; Suguru Tokiwa; Mitsuhiro Takeshita; Hiroto Nakano
Journal:  RSC Adv       Date:  2020-12-22       Impact factor: 3.361

Review 5.  Chiral Thioureas-Preparation and Significance in Asymmetric Synthesis and Medicinal Chemistry.

Authors:  Franz Steppeler; Dominika Iwan; Elżbieta Wojaczyńska; Jacek Wojaczyński
Journal:  Molecules       Date:  2020-01-18       Impact factor: 4.411
  5 in total

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