Literature DB >> 1833731

Determination of clarithromycin as a contaminant on surfaces by high-performance liquid chromatography using electrochemical detection.

T D Rotsch1, M Spanton, P Cugier, A C Plasz.   

Abstract

Microgram levels of clarithromycin residues on various surfaces are quantitated. After cleaning, any residual clarithromycin remaining is removed from the surface by a wet swab-dry swab technique. High-performance liquid chromatography with electrochemical detection is used for quantitation of the resulting solutions. Recoveries ranged from 93 to 118%.

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Year:  1991        PMID: 1833731     DOI: 10.1023/a:1015844705331

Source DB:  PubMed          Journal:  Pharm Res        ISSN: 0724-8741            Impact factor:   4.200


  1 in total

1.  Simplified method for determination of clarithromycin in human plasma using protein precipitation in a 96-well format and liquid chromatography-tandem mass spectrometry.

Authors:  Jaekyu Shin; Daniel F Pauly; Julie A Johnson; Reginald F Frye
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2008-07-05       Impact factor: 3.205

  1 in total

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