Literature DB >> 18337153

Deep brain stimulation of CM/PF of thalamus could be the new elective target for tremor in advanced Parkinson's Disease?

A Peppe1, A Gasbarra, A Stefani, C Chiavalon, M Pierantozzi, E Fermi, P Stanzione, C Caltagirone, P Mazzone.   

Abstract

Aim of this study was to investigate whether Deep Brain Stimulation (DBS) of the Centre Median Nucleus/Parafascicular (CM/PF) Complex is useful in reducing extrapyramidal symptoms in advanced Parkinson's Disease (PD) patients. In particular, we compared the action of CM/PF and subthalamic nucleus (STN) DBS on resting hand tremor using EMG surface of ulnar and radial right-hand muscles. Our results show that C/M DBS is very effective in reducing tremor, indicating this complex as a new target in advanced PD patients.

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Year:  2008        PMID： 18337153     DOI： 10.1016/j.parkreldis.2007.11.005

Source DB:  PubMed          Journal:  Parkinsonism Relat Disord        ISSN： 1353-8020            Impact factor:   4.891


  24 in total

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2.  Extracerebellar role for Cerebellin1: modulation of dendritic spine density and synapses in striatal medium spiny neurons.

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Review 4.  Selective GABA release as a mechanistic basis of high-frequency stimulation used for the treatment of neuropsychiatric diseases.

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5.  A review of basal ganglia circuits and physiology: Application to deep brain stimulation.

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Journal:  Parkinsonism Relat Disord       Date:  2019-01-09       Impact factor: 4.891

6.  Distinct Cortical-Thalamic-Striatal Circuits through the Parafascicular Nucleus.

Authors:  Gil Mandelbaum; Julian Taranda; Trevor M Haynes; Daniel R Hochbaum; Kee Wui Huang; Minsuk Hyun; Kannan Umadevi Venkataraju; Christoph Straub; Wengang Wang; Keiramarie Robertson; Pavel Osten; Bernardo L Sabatini
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7.  Deep brain stimulation of the centromedian thalamic nucleus for essential tremor: a case report.

Authors:  Vibhash D Sharma; Klaus Mewes; Thomas Wichmann; Cathrin Buetefisch; Jon T Willie; Mahlon DeLong
Journal:  Acta Neurochir (Wien)       Date:  2017-03-16       Impact factor: 2.216

8.  Is the loss of thalamostriatal neurons protective in parkinsonism?

Authors:  Sheila V Kusnoor; E Chris Muly; James I Morgan; Ariel Y Deutch
Journal:  Parkinsonism Relat Disord       Date:  2009-12       Impact factor: 4.891

9.  Pathway-Specific Remodeling of Thalamostriatal Synapses in Parkinsonian Mice.

Authors:  Philip R L Parker; Arnaud L Lalive; Anatol C Kreitzer
Journal:  Neuron       Date:  2016-01-28       Impact factor: 17.173

10.  Sub-synaptic localization of Cav3.1 T-type calcium channels in the thalamus of normal and parkinsonian monkeys.

Authors:  Erdong Chen; Jean-Francois Paré; Thomas Wichmann; Yoland Smith
Journal:  Brain Struct Funct       Date:  2016-06-02       Impact factor: 3.270
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