AIM: To analyze the influence of contrast dose adjusted by weight vs. fixed contrast dose in the attenuation and cost of abdominal computed tomography (CT). MATERIALS AND METHODS: A randomised, consecutive, parallel group study was conducted in 151 patients (74 men and 77 women, age range 22-67 years), studied with the same CT helical protocol. A dose at 1.75 ml/kg was administered in 101 patients while 50 patients had afixed dose of 120 ml of same non-ionic contrast material (320 mg/ml). Mean enhancements were measured at right hepatic lobe, superior abdominal aorta and inferior cava vein. Statistical analysis was weight-stratified (<60, 61-70, 71-80 and >81 kg). RESULTS:Aortic attenuation was significantly superior (p<0.05) in the dose adjusted by weight group than in the fixed dose group. Patients who weighed >61 kg in dose-adjusted group, presented higher hepatic attenuation, being statistically significant in those >81 kg (p<0.01). In dose-adjusted group, there was a savings of euro 4.1 per patient in patients weighing <80 kg. In patients weighing >80 kg, there was an over cost of euro 10.7 per patient. CONCLUSIONS: An injection volume of 1.75 ml/kg offers an optimal diagnostic quality with a global savings of euro 1.34 per patient.
RCT Entities:
AIM: To analyze the influence of contrast dose adjusted by weight vs. fixed contrast dose in the attenuation and cost of abdominal computed tomography (CT). MATERIALS AND METHODS: A randomised, consecutive, parallel group study was conducted in 151 patients (74 men and 77 women, age range 22-67 years), studied with the same CT helical protocol. A dose at 1.75 ml/kg was administered in 101 patients while 50 patients had a fixed dose of 120 ml of same non-ionic contrast material (320 mg/ml). Mean enhancements were measured at right hepatic lobe, superior abdominal aorta and inferior cava vein. Statistical analysis was weight-stratified (<60, 61-70, 71-80 and >81 kg). RESULTS: Aortic attenuation was significantly superior (p<0.05) in the dose adjusted by weight group than in the fixed dose group. Patients who weighed >61 kg in dose-adjusted group, presented higher hepatic attenuation, being statistically significant in those >81 kg (p<0.01). In dose-adjusted group, there was a savings of euro 4.1 per patient in patients weighing <80 kg. In patients weighing >80 kg, there was an over cost of euro 10.7 per patient. CONCLUSIONS: An injection volume of 1.75 ml/kg offers an optimal diagnostic quality with a global savings of euro 1.34 per patient.
Authors: Babs M F Hendriks; Madeleine Kok; Casper Mihl; Sebastiaan C A M Bekkers; Joachim E Wildberger; Marco Das Journal: Br J Radiol Date: 2016-01-22 Impact factor: 3.039
Authors: Simon Lennartz; Nils Große Hokamp; Charlotte Zäske; David Zopfs; Grischa Bratke; Andreas Glauner; David Maintz; Thorsten Persigehl; De-Hua Chang; Tilman Hickethier Journal: Br J Radiol Date: 2020-07-24 Impact factor: 3.039