Literature DB >> 18336804

Facile synthesis of methyl alpha- and beta-D-[6-(3)H]galactofuranosides from D-galacturonic acid. Substrates for the detection of galactofuranosidases.

Andrea Bordoni1, Carlos Lima, Karina Mariño, Rosa M de Lederkremer, Carla Marino.   

Abstract

Galactofuranose metabolism is a good target for the development of novel chemotherapeutic agents for the treatment of some microbial infections. A simple procedure for the synthesis of methyl (methyl alpha,beta-D-galactopyranosid)uronate followed by NaB(3)H(4) reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases.

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Year:  2008        PMID： 18336804     DOI： 10.1016/j.carres.2008.02.019

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN： 0008-6215            Impact factor:   2.104


  3 in total

1.  The endogenous galactofuranosidase GlfH1 hydrolyzes mycobacterial arabinogalactan.

Authors:  Lin Shen; Albertus Viljoen; Sydney Villaume; Maju Joe; Iman Halloum; Loïc Chêne; Alexandre Méry; Emeline Fabre; Kaoru Takegawa; Todd L Lowary; Stéphane P Vincent; Laurent Kremer; Yann Guérardel; Christophe Mariller
Journal:  J Biol Chem       Date:  2020-02-27       Impact factor: 5.157

2.  A biophysical study with carbohydrate derivatives explains the molecular basis of monosaccharide selectivity of the Pseudomonas aeruginosa lectin LecB.

Authors:  Roman Sommer; Thomas E Exner; Alexander Titz
Journal:  PLoS One       Date:  2014-11-21       Impact factor: 3.240

3.  Synthesis of a derivative of α-D-Glcp(1->2)-D-Galf suitable for further glycosylation and of α-D-Glcp(1->2)-D-Gal, a disaccharide fragment obtained from varianose.

Authors:  Carla Marino; Carlos Lima; Karina Mariño; Rosa M de Lederkremer
Journal:  Beilstein J Org Chem       Date:  2012-12-07       Impact factor: 2.883
  3 in total

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