Literature DB >> 18336375

Updates on bisphosphonates and potential pathobiology of bisphosphonate-induced jaw osteonecrosis.

J Sarin1, S S DeRossi, S O Akintoye.   

Abstract

Osteonecrosis of the jaws is a major complication associated with long-term use of bisphosphonates. While osteonecrosis can arise from other precipitating conditions, bisphosphonate-induced jaw osteonecrosis (BJON) is highly associated with long-term administration of pamidronate (Aredia) and zoledronic acid (Zometa), which are two intravenous bisphosphonate formulations. The underlying pathogenesis of BJON and its site-specific presentation still remain to be fully elucidated. This review will discuss clinically available bisphosphonates, current opinions, pathogenesis, and management guidelines for bisphosphonate-induced jaw osteonecrosis.

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Year:  2008        PMID： 18336375     DOI： 10.1111/j.1601-0825.2007.01381.x

Source DB:  PubMed          Journal:  Oral Dis        ISSN： 1354-523X            Impact factor:   3.511


  26 in total

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Authors:  Fred Saad; Sebastien J Hotte
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2.  Importance of microcracks in etiology of bisphosphonate-related osteonecrosis of the jaw: a possible pathogenetic model of symptomatic and non-symptomatic osteonecrosis of the jaw based on scanning electron microscopy findings.

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Journal:  Clin Oral Investig       Date:  2009-06-18       Impact factor: 3.573

3.  Osteoporosis treatment and medication-related osteonecrosis of the jaws.

Authors:  Christopher Daly
Journal:  Aust Prescr       Date:  2016-04-01

4.  Bisphosphonate-related osteonecrosis of jaws in advanced stage breast cancer was detected from bone scan: a case report.

Authors:  Prakasit Chirappapha; Saowanee Kitudomrat; Thanaporn Thongjood; Rangsima Aroonroch
Journal:  Gland Surg       Date:  2017-02

5.  Anatomic site variability in rat skeletal uptake and desorption of fluorescently labeled bisphosphonate.

Authors:  D Wen; L Qing; G Harrison; E Golub; S O Akintoye
Journal:  Oral Dis       Date:  2010-12-02       Impact factor: 3.511

6.  Osteo-radio-necrosis (ORN) and bisphosphonate-related osteonecrosis of the jaws (BRONJ): the histopathological differences under the clinical similarities.

Authors:  Konstantinos T Mitsimponas; Patrick Moebius; Kerstin Amann; Philipp Stockmann; Karl-Andreas Schlegel; Friedrich-Wilhelm Neukam; Falk Wehrhan
Journal:  Int J Clin Exp Pathol       Date:  2014-01-15

7.  Onset of mandible and tibia osteoradionecrosis: a comparative pilot study in the rat.

Authors:  Monika Damek-Poprawa; Stefan Both; Alexander C Wright; Amit Maity; Sunday O Akintoye
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol       Date:  2012-12-17

8.  Osteotomy and primary wound closure in bisphosphonate-associated osteonecrosis of the jaw: a prospective clinical study with 12 months follow-up.

Authors:  Philipp Stockmann; Eleftherios Vairaktaris; Falk Wehrhan; Martin Seiss; Stephan Schwarz; Bernd Spriewald; Friedrich-Wilhelm Neukam; Emeka Nkenke
Journal:  Support Care Cancer       Date:  2009-07-17       Impact factor: 3.603

Review 9.  Chemical and Radiation-Associated Jaw Lesions.

Authors:  Temitope T Omolehinwa; Sunday O Akintoye
Journal:  Dent Clin North Am       Date:  2016-01

10.  Bisphosphonate-Related Osteonecrosis of the Jaws and Its Array of Manifestations.

Authors:  Gustavo Davi Rabelo; José Narciso Rosa Assunção; Pascale Chavassieux; Haroldo Arid Soares; Fabio Abreu Alves; Celso Augusto Lemos
Journal:  J Maxillofac Oral Surg       Date:  2014-10-15
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