| Literature DB >> 18335810 |
V Bhanuprakash1, M Hosamani, V Balamurugan, P Gandhale, Ram Naresh, D Swarup, R K Singh.
Abstract
Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana (Jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.38 and 1999.73 +/- 0.50 microg/ml, respectively in all cytopathic effect (CPE) inhibition assays. Inhibition of GTPV virus replication was further confirmed by PCR and SYBR Green based quantitative real-time QPCR assays specific for GTPV. Results indicated that the extract of Acacia arabica and Eugenia jambolana leaves inhibited GTPV replication in vitro.Entities:
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Year: 2008 PMID： 18335810
Source DB: PubMed Journal: Indian J Exp Biol ISSN： 0019-5189 Impact factor: 0.818