Literature DB >> 18335320

Gene concepts and genethics: beyond exceptionalism.

Péter Kakuk1.   

Abstract

The discursive explosion that was provoked by the new genetics could support the impression that the ethical and social problems posed by the new genetics are somehow exceptional in their very nature. According to this view we are faced with special ethical and social problems that create a challenge so fundamental that the special label of genethics is needless to justify. The historical account regarding the evolution of the gene concepts could serve us to highlight the limits of what we know about genes and what we can do with genes. The widespread notion about the exceptionality of genetic knowledge and its applicative possibilities is hardly justifiable and leads to misunderstandings regarding the conceptualization of the ethical and social problems we might face. Following a more realistic interpretation of the role of genes in human life we might avoid a whole set of fictive dilemmas and counterproductive regulatory efforts in bioethics. Bioethical discourse should move from the gene-centered scientific discourse toward the more sophisticated and complex discourses where human development represented as a matter of complex interactions between genomes and environments, between genes, educational factors, nutritional regimes, and other different developmental resources. If a gene is seen as one among the different developmental resources that are shaping a given human trait then both genethics and genetic exceptionalism could hardly be represented as a justified approach in discussing the ethical and social problems of genetics.

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Year:  2008        PMID: 18335320     DOI: 10.1007/s11948-008-9056-7

Source DB:  PubMed          Journal:  Sci Eng Ethics        ISSN: 1353-3452            Impact factor:   3.525


  16 in total

1.  Informed consent in the genetic age.

Authors:  A Goldworth
Journal:  Camb Q Healthc Ethics       Date:  1999       Impact factor: 1.284

2.  Genetic testing: a conceptual exploration.

Authors:  R L Zimmern
Journal:  J Med Ethics       Date:  1999-04       Impact factor: 2.903

3.  The double helix 50 years on: models, metaphors, and reductionism.

Authors:  R E Ashcroft
Journal:  J Med Ethics       Date:  2003-04       Impact factor: 2.903

4.  Identification of genetic susceptibility to common diseases: the case for regulation.

Authors:  Patricia A Baird
Journal:  Perspect Biol Med       Date:  2002       Impact factor: 1.416

5.  Allosteric proteins and cellular control systems.

Authors:  J MONOD; J P CHANGEUX; F JACOB
Journal:  J Mol Biol       Date:  1963-04       Impact factor: 5.469

6.  Genetic regulatory mechanisms in the synthesis of proteins.

Authors:  F JACOB; J MONOD
Journal:  J Mol Biol       Date:  1961-06       Impact factor: 5.469

Review 7.  The evaluation of genetic tests.

Authors:  Ron L Zimmern; Mark Kroese
Journal:  J Public Health (Oxf)       Date:  2007-05-24       Impact factor: 2.341

Review 8.  The concept of the gene: short history and present status.

Authors:  P Portin
Journal:  Q Rev Biol       Date:  1993-06       Impact factor: 4.875

Review 9.  Splicing in the inner ear: a familiar tune, but what are the instruments?

Authors:  D L Black
Journal:  Neuron       Date:  1998-02       Impact factor: 17.173

10.  Definition of a gene.

Authors:  C D Epp
Journal:  Nature       Date:  1997-10-09       Impact factor: 49.962

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  5 in total

1.  Ethical signposts for clinical geneticists in secondary variant and incidental finding disclosure discussions.

Authors:  Gabrielle M Christenhusz; Koenraad Devriendt; Hilde Van Esch; Kris Dierickx
Journal:  Med Health Care Philos       Date:  2015-08

2.  Attitudes toward genetic research review: results from a survey of human genetics researchers.

Authors:  K L Edwards; A A Lemke; S B Trinidad; S M Lewis; H Starks; M T Quinn Griffin; G L Wiesner
Journal:  Public Health Genomics       Date:  2011-04-11       Impact factor: 2.000

3.  You never call, you never write: why return of 'omic' results to research participants is both a good idea and a moral imperative.

Authors:  Misha Angrist
Journal:  Per Med       Date:  2011-11       Impact factor: 2.512

4.  Genetic enhancement in sports: The role of reason and private rationalities in the public arena.

Authors:  Silvia Camporesi; Paolo Maugeri
Journal:  Camb Q Healthc Ethics       Date:  2011-04       Impact factor: 1.284

5.  Genetics specialists' perspectives on disclosure of genomic incidental findings in the clinical setting.

Authors:  Nancy R Downing; Janet K Williams; Sandra Daack-Hirsch; Martha Driessnack; Christian M Simon
Journal:  Patient Educ Couns       Date:  2012-10-12
  5 in total

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