Literature DB >> 18335179

[Multicentric randomised controlled trials in Germany: overview and interim analysis 1 year after inclusion of in the rubric "Clinical Trials"].

M N Wente1, L Fischer, C M Seiler.   

Abstract

BACKGROUND: For 1 year now, German surgical multicentric randomised controlled trials (MRCT) in Germany may be included under the heading "Clinical Trials" in our monthly updated trial list.
MATERIAL AND METHODS: Quantitative and qualitative analysis of MRCT presented in the trial list was performed to give an overview and interim statement 1 year after implementation of the journal heading "Clinical Trials".
RESULTS: In 1 year, the study list increased from four to eleven MRCT and the numbers of randomized patients from 396 to 1511. The MRCT show distinct differences regarding funding sources and reimbursement for participating centres per patient included. The study protocols of four of 11 MRCT were published in scientific journals.
CONCLUSION: The new regular heading gives important details about ongoing surgical trials in Germany. The steady growth of trials and recruited patients demonstrates the practicability of randomized controlled trials in surgery.

Entities:  

Mesh:

Year:  2008        PMID: 18335179     DOI: 10.1007/s00104-008-1508-8

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  8 in total

1.  [The LAPDIV-CAMIC Study. Multicenter prospective randomized study of short-term and intermediate-term outcome of laparoscopic and conventional sigmoid resection in diverticular disease].

Authors:  W Schwenk
Journal:  Chirurg       Date:  2004-07       Impact factor: 0.955

2.  Evaluation of criteria for temporary external fixation in risk-adapted damage control orthopedic surgery of femur shaft fractures in multiple trauma patients: "evidence-based medicine" versus "reality" in the trauma registry of the German Trauma Society.

Authors:  Dieter Rixen; Guido Grass; Stefan Sauerland; Rolf Lefering; Marcus R Raum; Nedim Yücel; Bertil Bouillon; Edmund A M Neugebauer
Journal:  J Trauma       Date:  2005-12

3.  [Recruiting multicenter surgical studies in Germany. Ongoing studies].

Authors:  M N Wente
Journal:  Chirurg       Date:  2007-04       Impact factor: 0.955

4.  Efficacy of different technical procedures for sentinel lymph node biopsy in gastric cancer staging.

Authors:  Stephan Gretschel; Andreas Bembenek; Michael Hünerbein; Stefan Dresel; Wolfgang Schneider; Peter M Schlag
Journal:  Ann Surg Oncol       Date:  2007-04-24       Impact factor: 5.344

5.  [Multicenter surgical studies recruiting in Germany. A new regular heading in the German surgical journal "Der Chirurg"].

Authors:  M N Wente; W Schwenk; C M Seiler
Journal:  Chirurg       Date:  2007-04       Impact factor: 0.955

6.  Protocol design and current status of CLIVIT: a randomized controlled multicenter relevance trial comparing clips versus ligatures in thyroid surgery.

Authors:  C M Seiler; B E Fröhlich; J A Veit; E Gazyakan; M N Wente; C Wollermann; A Deckert; S Witte; N Victor; M W Buchler; H P Knaebel
Journal:  Trials       Date:  2006-09-01       Impact factor: 2.279

7.  Comparison of total parathyroidectomy without autotransplantation and without thymectomy versus total parathyroidectomy with autotransplantation and with thymectomy for secondary hyperparathyroidism: TOPAR PILOT-Trial.

Authors:  Katja Schlosser; Johannes A Veit; Stefan Witte; Emilio Domínguez Fernández; Norbert Victor; Hans-Peter Knaebel; Christoph M Seiler; Matthias Rothmund
Journal:  Trials       Date:  2007-09-18       Impact factor: 2.279

8.  Acute cholecystitis - early laparoskopic surgery versus antibiotic therapy and delayed elective cholecystectomy: ACDC-study.

Authors:  Kilian Weigand; Jörg Köninger; Jens Encke; Markus W Büchler; Wolfgang Stremmel; Carsten N Gutt
Journal:  Trials       Date:  2007-10-04       Impact factor: 2.279

  8 in total
  1 in total

1.  [Column"clinical studies" - results of a reader survey].

Authors:  M N Wente; C M Seiler; J R Siewert
Journal:  Chirurg       Date:  2008-08       Impact factor: 0.955

  1 in total

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