Literature DB >> 1833343

Induction of Fc epsilon RII/CD23 on human T cells by excretory and secretory antigen of Dirofilaria immitis.

K A Yamaoka1, S Tsukidate, M Higaki, N Miyasaka, K Fujita.   

Abstract

We investigated the capacity of excretory and secretory antigen (ES) derived from living filarial worms in the induction of CD23 expression on human peripheral blood T cells by using flow cytometry. ES (10 micrograms/ml) significantly induced the expression of CD23 on human T cells. Moreover, increased CD23 expression was completely abolished by preincubation with specific antibody to ES. The results suggest that ES might play a certain role in IgE antibody production by induction of CD23 expression on T cells.

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Year:  1991        PMID: 1833343     DOI: 10.1159/000235460

Source DB:  PubMed          Journal:  Int Arch Allergy Appl Immunol        ISSN: 0020-5915


  1 in total

1.  Ivermectin-facilitated immunity in onchocerciasis. Reversal of lymphocytopenia, cellular anergy and deficient cytokine production after single treatment.

Authors:  P T Soboslay; C M Dreweck; W H Hoffmann; C G Lüder; C Heuschkel; H Görgen; M Banla; H Schulz-Key
Journal:  Clin Exp Immunol       Date:  1992-09       Impact factor: 4.330

  1 in total

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