Literature DB >> 18332715

Fish consumption, methylmercury and child neurodevelopment.

Emily Oken1, David C Bellinger.   

Abstract

PURPOSE OF REVIEW: To summarize recent evidence regarding associations of early life exposure to mercury from maternal fish consumption during pregnancy, thimerosal in vaccines and dental amalgam with child neurodevelopment. RECENT
FINDINGS: Recent publications have built upon previous evidence demonstrating mild detrimental neurocognitive effects from prenatal methylmercury exposure from maternal fish consumption during pregnancy. New studies examining the effects of prenatal fish consumption as well as methylmercury suggest there are benefits from prenatal fish consumption, but also that consumption of fish high in mercury should be avoided. Future studies incorporating information on both the methylmercury and the docosahexaenoic acid contained within fish will help to refine recommendations to optimize outcomes for mothers and children. Additional recent studies have supported the safety of vaccines containing thimerosal and of dental amalgam for repair of dental caries in children.
SUMMARY: Exposure to mercury may harm child development. Interventions intended to reduce exposure to low levels of mercury in early life must, however, be carefully evaluated in consideration of the potential attendant harm from resultant behavior changes, such as reduced docosahexaenoic acid exposure from lower seafood intake, reduced uptake of childhood vaccinations and suboptimal dental care.

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Year:  2008        PMID: 18332715      PMCID: PMC2581505          DOI: 10.1097/MOP.0b013e3282f5614c

Source DB:  PubMed          Journal:  Curr Opin Pediatr        ISSN: 1040-8703            Impact factor:   2.856


  41 in total

1.  A quantitative risk-benefit analysis of changes in population fish consumption.

Authors:  Joshua T Cohen; David C Bellinger; William E Connor; Penny M Kris-Etherton; Robert S Lawrence; David A Savitz; Bennett A Shaywitz; Steven M Teutsch; George M Gray
Journal:  Am J Prev Med       Date:  2005-11       Impact factor: 5.043

Review 2.  Neurotoxicity and molecular effects of methylmercury.

Authors:  A F Castoldi; T Coccini; S Ceccatelli; L Manzo
Journal:  Brain Res Bull       Date:  2001-05-15       Impact factor: 4.077

3.  A quantitative analysis of prenatal intake of n-3 polyunsaturated fatty acids and cognitive development.

Authors:  Joshua T Cohen; David C Bellinger; William E Connor; Bennett A Shaywitz
Journal:  Am J Prev Med       Date:  2005-11       Impact factor: 5.043

Review 4.  Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure.

Authors:  Wade V Welshons; Susan C Nagel; Frederick S vom Saal
Journal:  Endocrinology       Date:  2006-05-11       Impact factor: 4.736

5.  A docosahexaenoic acid-functional food during pregnancy benefits infant visual acuity at four but not six months of age.

Authors:  Michelle P Judge; Ofer Harel; Carol J Lammi-Keefe
Journal:  Lipids       Date:  2007-01-19       Impact factor: 1.880

6.  Associations of seafood and elongated n-3 fatty acid intake with fetal growth and length of gestation: results from a US pregnancy cohort.

Authors:  Emily Oken; Ken P Kleinman; Sjurdur F Olsen; Janet W Rich-Edwards; Matthew W Gillman
Journal:  Am J Epidemiol       Date:  2004-10-15       Impact factor: 4.897

7.  A dose-effect analysis of children's exposure to dental amalgam and neuropsychological function: the New England Children's Amalgam Trial.

Authors:  David C Bellinger; Felicia Trachtenberg; David Daniel; Annie Zhang; Mary A Tavares; Sonja McKinlay
Journal:  J Am Dent Assoc       Date:  2007-09       Impact factor: 3.634

8.  Maternal consumption of a docosahexaenoic acid-containing functional food during pregnancy: benefit for infant performance on problem-solving but not on recognition memory tasks at age 9 mo.

Authors:  Michelle P Judge; Ofer Harel; Carol J Lammi-Keefe
Journal:  Am J Clin Nutr       Date:  2007-06       Impact factor: 7.045

9.  An assessment of the impact of thimerosal on childhood neurodevelopmental disorders.

Authors:  David A Geier; Mark R Geier
Journal:  Pediatr Rehabil       Date:  2003 Apr-Jun

10.  Decline in fish consumption among pregnant women after a national mercury advisory.

Authors:  Emily Oken; Ken P Kleinman; Wendy E Berland; Steven R Simon; Janet W Rich-Edwards; Matthew W Gillman
Journal:  Obstet Gynecol       Date:  2003-08       Impact factor: 7.661

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  34 in total

1.  Childhood and adolescent fish consumption and adult neuropsychological performance: An analysis from the Cape Cod Health Study.

Authors:  Lindsey J Butler; Patricia A Janulewicz; Jenny L Carwile; Roberta F White; Michael R Winter; Ann Aschengrau
Journal:  Neurotoxicol Teratol       Date:  2017-03-03       Impact factor: 3.763

Review 2.  Neurotoxicity Linked to Dysfunctional Metal Ion Homeostasis and Xenobiotic Metal Exposure: Redox Signaling and Oxidative Stress.

Authors:  Carla Garza-Lombó; Yanahi Posadas; Liliana Quintanar; María E Gonsebatt; Rodrigo Franco
Journal:  Antioxid Redox Signal       Date:  2018-03-28       Impact factor: 8.401

Review 3.  The Putative Role of Environmental Mercury in the Pathogenesis and Pathophysiology of Autism Spectrum Disorders and Subtypes.

Authors:  G Morris; B K Puri; R E Frye; M Maes
Journal:  Mol Neurobiol       Date:  2017-07-22       Impact factor: 5.590

4.  Prenatal low-level mercury exposure and infant neurodevelopment at 12 months in rural northern China.

Authors:  Yi Hu; Limei Chen; Caifeng Wang; Yijun Zhou; Yan Zhang; Yiwen Wang; Rong Shi; Yu Gao; Ying Tian
Journal:  Environ Sci Pollut Res Int       Date:  2016-03-11       Impact factor: 4.223

5.  Association Between Midpregnancy Polyunsaturated Fatty Acid Levels and Offspring Autism Spectrum Disorder in a California Population-Based Case-Control Study.

Authors:  Kristen Lyall; Gayle C Windham; Nathaniel W Snyder; Rostislav Kuskovsky; Peining Xu; Anna Bostwick; Lucy Robinson; Craig J Newschaffer
Journal:  Am J Epidemiol       Date:  2021-02-01       Impact factor: 4.897

6.  Developmental exposure to methylmercury and resultant muscle mercury accumulation and adult motor deficits in mice.

Authors:  Matthew D Rand; Katherine Conrad; Elena Marvin; Katherine Harvey; Don Henderson; Rabi Tawil; Marissa Sobolewski; Deborah A Cory-Slechta
Journal:  Neurotoxicology       Date:  2020-07-28       Impact factor: 4.294

Review 7.  Neurobehavioural effects of developmental toxicity.

Authors:  Philippe Grandjean; Philip J Landrigan
Journal:  Lancet Neurol       Date:  2014-02-17       Impact factor: 44.182

Review 8.  Neurophysiologic measures of auditory function in fish consumers: associations with long chain polyunsaturated fatty acids and methylmercury.

Authors:  Adam C Dziorny; Mark S Orlando; J J Strain; Philip W Davidson; Gary J Myers
Journal:  Neurotoxicology       Date:  2012-10-12       Impact factor: 4.294

9.  Interaction between GSTM1/GSTT1 polymorphism and blood mercury on birth weight.

Authors:  Bo-Eun Lee; Yun-Chul Hong; Hyesook Park; Mina Ha; Bon Sang Koo; Namsoo Chang; Young-Man Roh; Boong-Nyun Kim; Young-Ju Kim; Byung-Mi Kim; Seong-Joon Jo; Eun-Hee Ha
Journal:  Environ Health Perspect       Date:  2010-03       Impact factor: 9.031

10.  Mercury exposure and a shift toward oxidative stress in avid seafood consumers.

Authors:  Roxanne Karimi; Caterina Vacchi-Suzzi; Jaymie R Meliker
Journal:  Environ Res       Date:  2015-12-30       Impact factor: 6.498

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