Literature DB >> 18331991

[Association between mitochondrial DNA mutations and cancer in human].

Shu-Ping Zhang1, Shu-Juan Song, Ya-Xuan Li.   

Abstract

Mitochondria are essential organelles that generate cellular energy in cells. Mutations of mitochondrial DNA (mtDNA) have been identified in various types of cancer, suggesting a complex relationship between mtDNA and cancer. This review focuses on the possible correlation between the mtDNA mutation and cancer. Additionally, possible causes for mtDNA mutations and applications for detecting mtDNA mutations in cancer are discussed.

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Year:  2008        PMID: 18331991     DOI: 10.3724/sp.j.1005.2008.00263

Source DB:  PubMed          Journal:  Yi Chuan        ISSN: 0253-9772


  1 in total

1.  Mitochondrial DNA content in paired normal and cancerous breast tissue samples from patients with breast cancer.

Authors:  Alex Xiu-Cheng Fan; Ramin Radpour; Mahdi Montazer Haghighi; Corina Kohler; Peng Xia; Sinuhe Hahn; Wolfgang Holzgreve; Xiao Yan Zhong
Journal:  J Cancer Res Clin Oncol       Date:  2009-01-06       Impact factor: 4.553

  1 in total

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