| Literature DB >> 18331048 |
Sujata Sengupta1, Haifeng Duan, Weibing Lu, Jeffrey L Petersen, Xiaodong Shi.
Abstract
A Lewis base-catalyzed three-component cascade reaction was developed for the synthesis of 4,5-disubstituted-1,2,3-(NH)-triazoles. More than 25 new (NH)-triazoles were prepared in good to excellent yields under mild conditions. The availability of the C-4 vinyl group allows easy conversion into other triazole derivatives.Entities:
Year: 2008 PMID: 18331048 DOI: 10.1021/ol8002783
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005