Literature DB >> 18330770

Use of pro re nata medications in acute inpatient care.

Jane Stein-Parbury1, Kim Reid, Narelle Smith, Diane Mouhanna, Fiona Lamont.   

Abstract

OBJECTIVES: Available evidence suggests that the use of 'as needed' (PRN; from the Latin pro re nata: for an occasion that has arisen) medications has remained a standard aspect of treatment in acute inpatient mental health units over a number of years despite lack of evidence from controlled clinical trials. The practice is one in which doctors and nurses are interdependent; that is, while doctors prescribe the medications, professional nurses are the ones who make the clinical decisions to administer them. The aim of the present study was to provide a detailed description of the circumstances surrounding the use of PRN medications across four inpatient units in Sydney.
METHODS: The medical records of all patients admitted for >24h during a 2 month period were retrospectively audited for details regarding prescriptions and administrations of PRN medications.
RESULTS: A total of 420 records were reviewed, producing a total of 3868 PRN medication administrations. Ninety-seven per cent of all patients were prescribed PRN medications and 93.8% were prescribed regular medications. The most frequently prescribed medications were second-generation antipsychotics for regular use along with benzodiazepine for PRN use. Nearly 84% of patients received at least one PRN medication during their admission, while patients diagnosed with personality disorder received more PRNs per day. The most common reason for PRN administration was patient agitation. The results indicated poor documentation in the prescription and documentation of PRN administrations. Also, the findings show that a small subset of the patients (5%) received >30% of all PRN medications.
CONCLUSION: PRN medication use has endured as standard practice and the results of the present study are consistent with the reported frequency of use increasing slightly over the years. The combination of second-generation antipsychotics as regular medications and benzodiazepines for PRN medication is consistent with recommended treatment guidelines. The small subset of patients who were overrepresented in the PRN administrations is noteworthy.

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Year:  2008        PMID: 18330770     DOI: 10.1080/00048670701881553

Source DB:  PubMed          Journal:  Aust N Z J Psychiatry        ISSN: 0004-8674            Impact factor:   5.744


  9 in total

1.  Discontinuing the Use of PRN Intramuscular Medication for Agitation in an Acute Psychiatric Hospital.

Authors:  Ariel Hayes; Mark J Russ
Journal:  Psychiatr Q       Date:  2016-03

2.  Pro re nata (as needed) psychotropic medication use in patients with borderline personality disorder and subjects with other personality disorders over 14 years of prospective follow-up.

Authors:  Eduardo Martinho; Garrett M Fitzmaurice; Frances R Frankenburg; Mary C Zanarini
Journal:  J Clin Psychopharmacol       Date:  2014-08       Impact factor: 3.153

3.  Measuring observed mental state in acute psychiatric inpatients.

Authors:  Ketrina A Sly; Terry J Lewin; Vaughan J Carr; Agatha M Conrad; Martin Cohen; Srinivasan Tirupati; Philip B Ward; Tim Coombs
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2008-08-23       Impact factor: 4.328

4.  Frequency, characteristics and management of adolescent inpatient aggression.

Authors:  Immaculada Baeza; Christoph U Correll; Ema Saito; Dinara Amanbekova; Meena Ramani; Sandeep Kapoor; Raja Chekuri; Marc De Hert; Maren Carbon
Journal:  J Child Adolesc Psychopharmacol       Date:  2013-05-06       Impact factor: 2.576

5.  Pro Re Nata Prescription and Perception Difference between Doctors and Nurses.

Authors:  Se Hwa Oh; Ji Eun Woo; Dong Woo Lee; Won Cheol Choi; Jong Lull Yoon; Mee Young Kim
Journal:  Korean J Fam Med       Date:  2014-07-25

6.  Does accreditation improve pro re nata benzodiazepines administration in psychiatric inpatients? Pre-post accreditation medical record comparison.

Authors:  Mohammed Abdullah Al-Sughayir
Journal:  Int J Ment Health Syst       Date:  2017-02-02

7.  Interventions following a high violence risk assessment score: a naturalistic study on a Finnish psychiatric admission ward.

Authors:  Jenni Kaunomäki; Markus Jokela; Raija Kontio; Tero Laiho; Eila Sailas; Nina Lindberg
Journal:  BMC Health Serv Res       Date:  2017-01-11       Impact factor: 2.655

8.  Practical Considerations of PRN Medicines Management: An Integrative Systematic Review.

Authors:  Abbas Mardani; Piret Paal; Christiane Weck; Shazia Jamshed; Mojtaba Vaismoradi
Journal:  Front Pharmacol       Date:  2022-04-12       Impact factor: 5.988

9.  Safewards: the empirical basis of the model and a critical appraisal.

Authors:  L Bowers; J Alexander; H Bilgin; M Botha; C Dack; K James; M Jarrett; D Jeffery; H Nijman; J A Owiti; C Papadopoulos; J Ross; S Wright; D Stewart
Journal:  J Psychiatr Ment Health Nurs       Date:  2014-01-24       Impact factor: 2.952

  9 in total

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