Literature DB >> 18330469

Antiepileptic drug transport--of mice and men.

Graeme J Sills.   

Abstract

Entities:  

Year:  2008        PMID： 18330469      PMCID： PMC2265805          DOI： 10.1111/j.1535-7511.2008.00234.x

Source DB:  PubMed          Journal:  Epilepsy Curr        ISSN： 1535-7511            Impact factor:   7.500


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  14 in total

1.  Valproic acid is not a substrate for P-glycoprotein or multidrug resistance proteins 1 and 2 in a number of in vitro and in vivo transport assays.

Authors:  Steffen Baltes; Maren Fedrowitz; Carlos Luna Tortós; Heidrun Potschka; Wolfgang Löscher
Journal:  J Pharmacol Exp Ther       Date:  2006-10-16       Impact factor: 4.030

2.  Limited P-glycoprotein mediated efflux for anti-epileptic drugs.

Authors:  Andrew Crowe; Yee-Khuan Teoh
Journal:  J Drug Target       Date:  2006-06       Impact factor: 5.121

3.  In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats.

Authors:  H Potschka; W Löscher
Journal:  Epilepsia       Date:  2001-10       Impact factor: 5.864

Review 4.  Drug resistance in brain diseases and the role of drug efflux transporters.

Authors:  Wolfgang Löscher; Heidrun Potschka
Journal:  Nat Rev Neurosci       Date:  2005-08       Impact factor: 34.870

5.  P-glycoprotein-mediated efflux of antiepileptic drugs: preliminary studies in mdr1a knockout mice.

Authors:  Graeme J. Sills; Patrick Kwan; Elaine Butler; Elizabeth C.M. de Lange; Dirk Jan van den Berg; Martin J. Brodie
Journal:  Epilepsy Behav       Date:  2002-10       Impact factor: 2.937

6.  P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

Authors:  A H Schinkel; E Wagenaar; C A Mol; L van Deemter
Journal:  J Clin Invest       Date:  1996-06-01       Impact factor: 14.808

7.  Inhibition of multidrug transporters by verapamil or probenecid does not alter blood-brain barrier penetration of levetiracetam in rats.

Authors:  Heidrun Potschka; Steffen Baltes; Wolfgang Löscher
Journal:  Epilepsy Res       Date:  2004-02       Impact factor: 3.045

8.  Interaction of antiepileptic drugs with human P-glycoprotein in vitro.

Authors:  Johanna Weiss; Christian Johannes Kerpen; Heike Lindenmaier; Sven-Maria Gregor Dormann; Walter Emil Haefeli
Journal:  J Pharmacol Exp Ther       Date:  2003-09-03       Impact factor: 4.030

9.  MDR1 gene expression in brain of patients with medically intractable epilepsy.

Authors:  D M Tishler; K I Weinberg; D R Hinton; N Barbaro; G M Annett; C Raffel
Journal:  Epilepsia       Date:  1995-01       Impact factor: 5.864

10.  Limbic seizures induce P-glycoprotein in rodent brain: functional implications for pharmacoresistance.

Authors:  Massimo Rizzi; Silvio Caccia; Giovanna Guiso; Cristina Richichi; Jan A Gorter; Eleonora Aronica; Marisa Aliprandi; Renzo Bagnati; Roberto Fanelli; Maurizio D'Incalci; Rosario Samanin; Annamaria Vezzani
Journal:  J Neurosci       Date:  2002-07-15       Impact factor: 6.167
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