Literature DB >> 18329610

A new antituberculosis drug that selectively kills nonmultiplying Mycobacterium tuberculosis.

Denis A Mitchison1.   

Abstract

An important report by Bryk et al. in this issue of Cell Host & Microbe describes the properties of a rhodanine prodrug active against nonmultiplying Mycobacterium tuberculosis (Mtb). Considering the tolerance of nonreplicating Mtb to most currently available agents, such a drug could be a major addition to our antituberculosis arsenal and would greatly benefit control of the disease.

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Year:  2008        PMID: 18329610     DOI: 10.1016/j.chom.2008.02.013

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN: 1931-3128            Impact factor:   21.023


  2 in total

Review 1.  Advances in adjunct therapy against tuberculosis: Deciphering the emerging role of phytochemicals.

Authors:  Samreen Fatima; Anjna Kumari; Ved Prakash Dwivedi
Journal:  MedComm (2020)       Date:  2021-08-05

2.  Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii-Mycobacterium marinum host-pathogen system.

Authors:  Sébastien Kicka; Valentin Trofimov; Christopher Harrison; Hajer Ouertatani-Sakouhi; John McKinney; Leonardo Scapozza; Hubert Hilbi; Pierre Cosson; Thierry Soldati
Journal:  PLoS One       Date:  2014-01-31       Impact factor: 3.240

  2 in total

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