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Literature DB >> 18328747

Asymmetric stem cell division: lessons from Drosophila.

Pao-Shu Wu¹, Boris Egger, Andrea H Brand.

Abstract

Asymmetric cell division is an important and conserved strategy in the generation of cellular diversity during animal development. Many of our insights into the underlying mechanisms of asymmetric cell division have been gained from Drosophila, including the establishment of polarity, orientation of mitotic spindles and segregation of cell fate determinants. Recent studies are also beginning to reveal the connection between the misregulation of asymmetric cell division and cancer. What we are learning from Drosophila as a model system has implication both for stem cell biology and also cancer research.

Entities: Chemical

Mesh：

Year: 2008 PMID： 18328747 DOI： 10.1016/j.semcdb.2008.01.007

Source DB: PubMed Journal: Semin Cell Dev Biol ISSN： 1084-9521 Impact factor: 7.727

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Cited

20 in total

1. Symmetric and asymmetric mitotic segregation patterns influence Wolbachia distribution in host somatic tissue.

Authors: Roger Albertson; Catharina Casper-Lindley; Jian Cao; Uyen Tram; William Sullivan
Journal: J Cell Sci Date: 2009-11-24 Impact factor: 5.285

2. The BASL polarity protein controls a MAPK signaling feedback loop in asymmetric cell division.

Authors: Ying Zhang; Pengcheng Wang; Wanchen Shao; Jian-Kang Zhu; Juan Dong
Journal: Dev Cell Date: 2015-04-02 Impact factor: 12.270

3. The SCFSlimb E3 ligase complex regulates asymmetric division to inhibit neuroblast overgrowth.

Authors: Song Li; Cheng Wang; Edwin Sandanaraj; Sherry S Y Aw; Chwee T Koe; Jack J L Wong; Fengwei Yu; Beng T Ang; Carol Tang; Hongyan Wang
Journal: EMBO Rep Date: 2014-01-10 Impact factor: 8.807

4. Regulation of Drosophila intestinal stem cell maintenance and differentiation by the transcription factor Escargot.

Authors: Mariano A Loza-Coll; Tony D Southall; Sharsti L Sandall; Andrea H Brand; D Leanne Jones
Journal: EMBO J Date: 2014-11-27 Impact factor: 11.598

5. Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila.

Authors: Yingshi Ouyang; Claudia Petritsch; Hong Wen; Lily Jan; Yuh Nung Jan; Bingwei Lu
Journal: Development Date: 2011-06 Impact factor: 6.868

Asymmetric stem cell division: lessons from Drosophila.

1. Symmetric and asymmetric mitotic segregation patterns influence Wolbachia distribution in host somatic tissue.

2. The BASL polarity protein controls a MAPK signaling feedback loop in asymmetric cell division.

3. The SCFSlimb E3 ligase complex regulates asymmetric division to inhibit neuroblast overgrowth.

4. Regulation of Drosophila intestinal stem cell maintenance and differentiation by the transcription factor Escargot.

5. Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila.

Review 6. Keeping neural progenitor cells on a short leash during Drosophila neurogenesis.

7. Apical polarity protein PrkCi is necessary for maintenance of spinal cord precursors in zebrafish.

8. Molecular characteristics of cancer stem-like cells derived from human breast cancer cells.

Review 9. Endocytosis, asymmetric cell division, stem cells and cancer: unus pro omnibus, omnes pro uno.

10. Capacity for stochastic self-renewal and differentiation in mammalian spermatogonial stem cells.