PURPOSE: To identify and quantify risk factors associated with preterm birth, stratified by gestational age at birth. METHODS: Three case-control analyses were done. Controls were pregnancies of > or =37 weeks of gestational age at birth. Cases were defined as: <28, 28-32, 33- <37 weeks of gestational age at birth respectively in the three case-control analyses. Women were categorized according to whether they carried single or multiple infants. RESULTS: Obstetrical conditions (placenta previa, placental abruption), and maternal hypertension were significantly associated with preterm delivery in all case-control analyses (adjusted OR between 1.34-19.56, p < 0.05). Leading risk factors for preterm delivery in singleton pregnancies were placental abruption and placenta previa (adjusted ORs 4.85 and 4.13, p < 0.05). For multiple pregnancies they were polyhydramnios and maternal hypertension (adjusted ORs 4.39 and 2.45, p < 0.05). CONCLUSIONS: Obstetrical conditions during the pregnancy and maternal hypertension are important risk factors for preterm birth.
PURPOSE: To identify and quantify risk factors associated with preterm birth, stratified by gestational age at birth. METHODS: Three case-control analyses were done. Controls were pregnancies of > or =37 weeks of gestational age at birth. Cases were defined as: <28, 28-32, 33- <37 weeks of gestational age at birth respectively in the three case-control analyses. Women were categorized according to whether they carried single or multiple infants. RESULTS: Obstetrical conditions (placenta previa, placental abruption), and maternal hypertension were significantly associated with preterm delivery in all case-control analyses (adjusted OR between 1.34-19.56, p < 0.05). Leading risk factors for preterm delivery in singleton pregnancies were placental abruption and placenta previa (adjusted ORs 4.85 and 4.13, p < 0.05). For multiple pregnancies they were polyhydramnios and maternal hypertension (adjusted ORs 4.39 and 2.45, p < 0.05). CONCLUSIONS: Obstetrical conditions during the pregnancy and maternal hypertension are important risk factors for preterm birth.
Authors: Jonathan G Shaw; D Alan Nelson; Kate A Shaw; Kelly Woolaway-Bickel; Ciaran S Phibbs; Lianne M Kurina Journal: Am J Epidemiol Date: 2018-04-01 Impact factor: 4.897
Authors: David M Ferrero; Jim Larson; Bo Jacobsson; Gian Carlo Di Renzo; Jane E Norman; James N Martin; Mary D'Alton; Ernesto Castelazo; Chris P Howson; Verena Sengpiel; Matteo Bottai; Jonathan A Mayo; Gary M Shaw; Ivan Verdenik; Nataša Tul; Petr Velebil; Sarah Cairns-Smith; Hamid Rushwan; Sabaratnam Arulkumaran; Jennifer L Howse; Joe Leigh Simpson Journal: PLoS One Date: 2016-09-13 Impact factor: 3.240