BACKGROUND: Lymphadenomatous carcinoma of the salivary gland is a very rare tumor, which hitherto occurred exclusively in the parotid gland. This report describes a case of lymphadenomatous carcinoma of the sublingual gland, which is thought to be the first report of this special entity. METHODS AND RESULTS: A 36-year-old man was seen with slowly growing mass on his right floor of mouth. Upon surgical removal, the mass was well encapsulated. Microscopic examination revealed a biphasic appearance with islands of neoplastic epithelial cells presenting against a dense lymphoid stroma, while the epithelial compartment showed features of malignancy. During 30-months of close follow-up, there has not been any sign of local recurrence or metastasis. CONCLUSION: The clinical behavior, the age of the patient, and the sublingual localization differentiate this lesion from the sebaceous type, favoring lymphadenomatous carcinoma as a distinct clinical entity. Copyright (c) 2008 Wiley Periodicals, Inc. Head Neck 2008.
BACKGROUND:Lymphadenomatous carcinoma of the salivary gland is a very rare tumor, which hitherto occurred exclusively in the parotid gland. This report describes a case of lymphadenomatous carcinoma of the sublingual gland, which is thought to be the first report of this special entity. METHODS AND RESULTS: A 36-year-old man was seen with slowly growing mass on his right floor of mouth. Upon surgical removal, the mass was well encapsulated. Microscopic examination revealed a biphasic appearance with islands of neoplastic epithelial cells presenting against a dense lymphoid stroma, while the epithelial compartment showed features of malignancy. During 30-months of close follow-up, there has not been any sign of local recurrence or metastasis. CONCLUSION: The clinical behavior, the age of the patient, and the sublingual localization differentiate this lesion from the sebaceous type, favoring lymphadenomatous carcinoma as a distinct clinical entity. Copyright (c) 2008 Wiley Periodicals, Inc. Head Neck 2008.
Authors: Nolan B Seim; Ramez H W Philips; Lynn Schoenfield; Theodoros N Teknos; James W Rocco; Amit Agrawal; Enver Ozer; Ricardo L Carrau; Stephen Y Kang; Matthew O Old Journal: Head Neck Pathol Date: 2017-03-27