Literature DB >> 18327323

Efficient palladium-catalyzed synthesis of 3-aryl-4-indolylmaleimides.

Anahit Pews-Davtyan1, Annegret Tillack, Stefanie Ortinau, Arndt Rolfs, Matthias Beller.   

Abstract

Improved palladium catalysts for the Suzuki coupling of 3-bromo-1-methyl-4-(2-methyl-3-indolyl)maleimide have been developed. The coupling of both aryl- and heteroarylboronic acids proceeds smoothly in good to excellent yields at low catalyst loading.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18327323     DOI： 10.1039/b719160j

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

1.  The novel arylindolylmaleimide PDA-66 displays pronounced antiproliferative effects in acute lymphoblastic leukemia cells.

Authors:  Christin Kretzschmar; Catrin Roolf; Tina-Susann Langhammer; Anett Sekora; Anahit Pews-Davtyan; Matthias Beller; Moritz J Frech; Christian Eisenlöffel; Arndt Rolfs; Christian Junghanss
Journal:  BMC Cancer       Date:  2014-02-06       Impact factor: 4.430

2.  BF3-OEt2 Catalyzed C3-Alkylation of Indole: Synthesis of Indolylsuccinimidesand Their Cytotoxicity Studies.

Authors:  Iqbal N Shaikh; Abdul Rahim; Shaikh Faazil; Syed Farooq Adil; Mohamed E Assal; Mohammad Rafe Hatshan
Journal:  Molecules       Date:  2021-04-11       Impact factor: 4.411

3.  PDA Indolylmaleimides Induce Anti-Tumor Effects in Prostate Carcinoma Cell Lines Through Mitotic Death.

Authors:  Jan Torben Schille; Ingo Nolte; Julia Beck; Daria Jilani; Catrin Roolf; Anahit Pews-Davtyan; Arndt Rolfs; Larissa Henze; Matthias Beller; Bertram Brenig; Christian Junghanss; Ekkehard Schütz; Hugo Murua Escobar
Journal:  Front Vet Sci       Date:  2021-01-20

4.  A Simple LC-MS/MS Method for the Quantification of PDA-66 in Human Plasma.

Authors:  Rico Schwarz; Elisabeth R D Seiler; Sina Sender; Anahit Pews-Davtyan; Hugo Murua Escobar; Dietmar Zechner; Matthias Beller; Christian Junghanß; Burkhard Hinz
Journal:  Molecules       Date:  2022-02-01       Impact factor: 4.411
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.