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Literature DB >> 18324975

Clinical effectiveness of decitabine in severe sickle cell disease.

Yogen Saunthararajah, Robert Molokie, Santosh Saraf, Seema Sidhwani, Michel Gowhari, Steven Vara, Donald Lavelle, Joseph DeSimone.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2008 PMID： 18324975 DOI： 10.1111/j.1365-2141.2008.07027.x

Source DB: PubMed Journal: Br J Haematol ISSN： 0007-1048 Impact factor: 6.998

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22 in total

1. Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus.

Authors: Zhenbo Hu; Soledad Negrotto; Xiaorong Gu; Reda Mahfouz; Kwok Peng Ng; Quteba Ebrahem; Edward Copelan; Harinder Singh; Jaroslaw P Maciejewski; Yogen Saunthararajah
Journal: Mol Cancer Ther Date: 2010-05-25 Impact factor: 6.261

Review 2. Fetal hemoglobin in sickle cell anemia: The Arab-Indian haplotype and new therapeutic agents.

Authors: Alawi H Habara; Elmutaz M Shaikho; Martin H Steinberg
Journal: Am J Hematol Date: 2017-08-17 Impact factor: 10.047

3. The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice.

Authors: Shuaiying Cui; Kim-Chew Lim; Lihong Shi; Mary Lee; Natee Jearawiriyapaisarn; Greggory Myers; Andrew Campbell; David Harro; Shigeki Iwase; Raymond C Trievel; Angela Rivers; Joseph DeSimone; Donald Lavelle; Yogen Saunthararajah; James Douglas Engel
Journal: Blood Date: 2015-06-01 Impact factor: 22.113

Review 4. Clinical development of demethylating agents in hematology.

Authors: Shyamala C Navada; Juliane Steinmann; Michael Lübbert; Lewis R Silverman
Journal: J Clin Invest Date: 2014-01-02 Impact factor: 14.808

5. Noncytotoxic differentiation treatment of renal cell cancer.

Authors: Soledad Negrotto; Zhenbo Hu; Oscar Alcazar; Kwok Peng Ng; Pierre Triozzi; Daniel Lindner; Brian Rini; Yogen Saunthararajah
Journal: Cancer Res Date: 2011-02-08 Impact factor: 12.701

6. Simvastatin and t-butylhydroquinone suppress KLF1 and BCL11A gene expression and additively increase fetal hemoglobin in primary human erythroid cells.

Authors: Elizabeth R Macari; Emily K Schaeffer; Rachel J West; Christopher H Lowrey
Journal: Blood Date: 2012-12-06 Impact factor: 22.113

7. S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis).

Authors: Donald Lavelle; Yogen Saunthararajah; Kestis Vaitkus; Mahipal Singh; Virryan Banzon; Pasit Phiasivongsva; Sanjeev Redkar; Sarath Kanekal; David Bearss; Chongtie Shi; Roger Inloes; Joseph DeSimone
Journal: J Transl Med Date: 2010-10-08 Impact factor: 5.531