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Literature DB >> 18323732

Reduced cytokine production by glycogen-elicited peritoneal cells from diabetic rats.

Tatiana Carolina Alba-Loureiro¹, Tania Cristina Pithon-Curi, Rui Curi.

Abstract

IL-1beta, TNF-alpha, cytokine-induced neutrophil chemoattractant-2alpha/beta, and IL-10 measurements were performed in elicited peritoneal cells from control, diabetic, and insulin-treated diabetic rats. Production/liberation of these cytokines was decreased in elicited peritoneal cells from diabetic rats. These changes were abolished by insulin treatment of diabetic rats. The alterations observed might be involved in the impaired inflammatory response and high occurrence of apoptosis observed in neutrophils under diabetic states.

Entities: Chemical Disease Gene Species

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Year: 2008 PMID： 18323732 DOI： 10.1097/SHK.0b013e318164e834

Source DB: PubMed Journal: Shock ISSN： 1073-2322 Impact factor: 3.454

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Cited

5 in total

Reduced cytokine production by glycogen-elicited peritoneal cells from diabetic rats.

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Review 4. The Peritoneal Macrophages in Inflammatory Diseases and Abdominal Cancers.

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