Literature DB >> 18321714

Antifungal and antimycobacterial activity of 1-(3,5-diaryl-4,5-dihydro-1H-pyrazol-4-yl)-1H-imidazole derivatives.

Daniele Zampieri1, Maria Grazia Mamolo, Erik Laurini, Giuditta Scialino, Elena Banfi, Luciano Vio.   

Abstract

1-(3,5-Diaryl-4,5-dihydro-1H-pyrazol-4-yl)-1H-imidazole derivatives were synthesized and tested for their in vitro antifungal and antimycobacterial activities. These imidazole derivatives showed an excellent antifungal activity against a clinical strain of Candida albicans and an interesting antitubercular activity against Mycobacterium tuberculosis H(37)Rv reference strain.

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Year:  2008        PMID： 18321714     DOI： 10.1016/j.bmc.2008.02.055

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  7 in total

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  7 in total

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