Literature DB >> 18320211

Analysis of POSSUM score and postoperative morbidity in patients with rectal cancer undergoing surgery.

V Valenti1, J L Hernandez-Lizoain, J Baixauli, C Pastor, F Martinez-Regueira, J J Beunza, J J Aristu, J Alvarez Cienfuegos.   

Abstract

BACKGROUND: The Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) and later modifications (P-POSSUM y CR-POSSUM) have been used to predict morbidity and mortality rates among patients with rectal cancer undergoing surgery. These calculations need some adjustment, however. The aim of this study was to assess the applicability of POSSUM to a group of patients with rectal cancer undergoing surgery, analysing surgical morbidity by means of several variables.
METHODS: between January 1995 and December 2004, 273 consecutive patients underwent surgery for rectal cancer. Information was gathered about the patients, tumour and therapy. To assess the prediction capacity of POSSUM, subgroups for analysis were created according to variables related to operative morbidity and mortality.
RESULTS: The global morbidity rate was 23.6% (31.2% predicted by POSSUM). The mortality rate was 0.7% (6.64, 1.95 and 2.08 predicted by POSSUM, P-POSSUM and CR-POSSUM respectively). POSSUM predictions may be more accurate for patients younger than 51 years, older than 70 years, with low anaesthetic risk (ASA I/II), DUKES stage C and D, surgery duration of less than 180 minutes and for those receiving neoadjuvant therapy.
CONCLUSION: POSSUM is a good instrument to make results between different institutions and publication comparable. We found prediction errors for some variables related to morbidity. Modifications of surgical variables and specifications for neoadjuvant therapy as well as physiological variables including life style may improve future prediction of surgical risk. More research is needed to identify further potential risk factors for surgical complications.

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Year:  2008        PMID: 18320211     DOI: 10.1007/s00423-008-0314-6

Source DB:  PubMed          Journal:  Langenbecks Arch Surg        ISSN: 1435-2443            Impact factor:   3.445


  38 in total

1.  Surgical patients with methicillin resistant staphylococcus aureus infection: an analysis of outcome using P-POSSUM.

Authors:  K V Menon; M S Whiteley; P Burden; R B Galland
Journal:  J R Coll Surg Edinb       Date:  1999-06

2.  The role of anesthesia in surgical mortality.

Authors:  R D DRIPPS; A LAMONT; J E ECKENHOFF
Journal:  JAMA       Date:  1961-10-21       Impact factor: 56.272

3.  Evaluation of outcome of laparoscopic colorectal resection with POSSUM, Portsmouth POSSUM and colorectal POSSUM.

Authors:  W L Law; C M Lam; Y M Lee
Journal:  Br J Surg       Date:  2006-01       Impact factor: 6.939

4.  POSSUM and Portsmouth POSSUM for predicting mortality. Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity.

Authors:  D R Prytherch; M S Whiteley; B Higgins; P C Weaver; W G Prout; S J Powell
Journal:  Br J Surg       Date:  1998-09       Impact factor: 6.939

5.  Comparative audit of colorectal resection with the POSSUM scoring system.

Authors:  P M Sagar; M N Hartley; B Mancey-Jones; P C Sedman; J May; J Macfie
Journal:  Br J Surg       Date:  1994-10       Impact factor: 6.939

6.  Mortality, morbidity, and patterns of recurrence after abdominoperineal resection for cancer of the rectum.

Authors:  L Rosen; M C Veidenheimer; J A Coller; M L Corman
Journal:  Dis Colon Rectum       Date:  1982-04       Impact factor: 4.585

Review 7.  Risk scoring in surgical patients.

Authors:  H J Jones; L de Cossart
Journal:  Br J Surg       Date:  1999-02       Impact factor: 6.939

8.  Application of the POSSUM system in bariatric surgery.

Authors:  J C Cagigas; C F Escalante; A Ingelmo; R Hernandez-Estefania; F Hernanz; J Castillo; M G Fleitas
Journal:  Obes Surg       Date:  1999-06       Impact factor: 4.129

9.  POSSUM, p-POSSUM, and Cr-POSSUM: implementation issues in a United States health care system for prediction of outcome for colon cancer resection.

Authors:  Anthony J Senagore; Anthony J Warmuth; Conor P Delaney; Paris P Tekkis; Victor W Fazio
Journal:  Dis Colon Rectum       Date:  2004-07-15       Impact factor: 4.585

10.  Preoperative chemotherapy and radiation therapy for locally advanced primary and recurrent rectal carcinoma. A report of surgical morbidity.

Authors:  C R Shumate; T A Rich; J M Skibber; J A Ajani; D M Ota
Journal:  Cancer       Date:  1993-06-01       Impact factor: 6.860

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  6 in total

1.  Risk adjustment as basis for rational benchmarking: the example of colon carcinoma.

Authors:  Henry Ptok; Frank Marusch; Uwe Schmidt; Ingo Gastinger; Hubertus J C Wenisch; Hans Lippert
Journal:  World J Surg       Date:  2011-01       Impact factor: 3.352

Review 2.  A systematic review of POSSUM and its related models as predictors of post-operative mortality and morbidity in patients undergoing surgery for colorectal cancer.

Authors:  Colin Hewitt Richards; Fiona E Leitch; Paul G Horgan; Donald C McMillan
Journal:  J Gastrointest Surg       Date:  2010-09-08       Impact factor: 3.452

3.  Analysis of surgical complications of primary tumor resection after neoadjuvant treatment in stage IV colon cancer.

Authors:  Jorge Arredondo; Patricia Martínez; Jorge Baixauli; Carlos Pastor; Javier Rodríguez; Fernando Pardo; Fernando Rotellar; Ana Chopitea; José Luís Hernández-Lizoáin
Journal:  J Gastrointest Oncol       Date:  2014-04

4.  The relationship between patient physiology, the systemic inflammatory response and survival in patients undergoing curative resection of colorectal cancer.

Authors:  C H Richards; E F Leitch; P G Horgan; J H Anderson; R F McKee; D C McMillan
Journal:  Br J Cancer       Date:  2010-09-28       Impact factor: 7.640

Review 5.  Evaluation of a Modified POSSUM Scoring System for Predicting the Morbidity in Patients Undergoing Lumbar Surgery.

Authors:  Li Ying; Bai Bo; Wu Huo-Yan; Zhuang Hong
Journal:  Indian J Surg       Date:  2013-02-05       Impact factor: 0.656

6.  Validity of the CR-POSSUM model in surgery for colorectal cancer in Spain (CCR-CARESS study) and comparison with other models to predict operative mortality.

Authors:  Marisa Baré; Manuel Jesús Alcantara; Maria José Gil; Pablo Collera; Marina Pont; Antonio Escobar; Cristina Sarasqueta; Maximino Redondo; Eduardo Briones; Paula Dujovne; Jose Maria Quintana
Journal:  BMC Health Serv Res       Date:  2018-01-29       Impact factor: 2.655

  6 in total

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