Literature DB >> 18320007

One-pot synthesis of polysubstituted indoles from aliphatic nitro compounds under mild conditions.

Christopher A Simoneau1, Alexis M Strohl, Bruce Ganem.   

Abstract

Polysubstituted indoles can be prepared directly from functionalized nitroalkanes under very mildly acidic conditions in a simple, one-pot, two-stage procedure.

Entities:  

Year:  2007        PMID: 18320007      PMCID: PMC1855094          DOI: 10.1016/j.tetlet.2007.01.031

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN: 0040-4039            Impact factor:   2.415


  3 in total

Review 1.  Simple indole alkaloids and those with a nonrearranged monoterpenoid unit.

Authors:  S Hibino; T Choshi
Journal:  Nat Prod Rep       Date:  2001-02       Impact factor: 13.423

Review 2.  Conjugate additions of nitroalkanes to electron-poor alkenes: recent results.

Authors:  Roberto Ballini; Giovanna Bosica; Dennis Fiorini; Alessandro Palmieri; Marino Petrini
Journal:  Chem Rev       Date:  2005-03       Impact factor: 60.622

3.  A new synthesis of indole 5-carboxylic acids and 6-hydroxy-indole-5-carboxylic acids in the preparation of an o-hydroxylated metabolite of vilazodone.

Authors:  Timo Heinrich; Henning Böttcher
Journal:  Bioorg Med Chem Lett       Date:  2004-05-17       Impact factor: 2.823

  3 in total
  2 in total

1.  Studies on the synthesis of amidoximes from nitroalkanes.

Authors:  Gabriella Sanguineti; Hoang V Le; Bruce Ganem
Journal:  Tetrahedron       Date:  2011-12-30       Impact factor: 2.457

2.  Strategies for innovation in multicomponent reaction design.

Authors:  Bruce Ganem
Journal:  Acc Chem Res       Date:  2009-03-17       Impact factor: 22.384

  2 in total

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