Literature DB >> 18319288

Contribution of viral and cellular cytokines to Kaposi's sarcoma-associated herpesvirus pathogenesis.

Paola Gasperini1, Shuhei Sakakibara, Giovanna Tosato.   

Abstract

Kaposi's sarcoma (KS)-associated herpesvirus is associated with the proliferative/malignant disorders KS, primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD) in patients with AIDS. In spite of recent advances in the treatment of KS, PEL and MCD represent therapeutic challenges. Recent advances in dissecting the pathogenesis of these diseases have indicated that the viral cytokine IL-6 and the cellular cytokines/growth factors IL-10, IL-6, stromal cell-derived factor 1, and vascular endothelial growth factor are important contributors to the growth, survival, and spread of PEL and MCD and are therefore potential targets for drug development.

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Year:  2008        PMID： 18319288      PMCID： PMC2538598          DOI： 10.1189/jlb.1107777

Source DB:  PubMed          Journal:  J Leukoc Biol        ISSN： 0741-5400            Impact factor:   4.962


  57 in total

1.  Detection of vascular endothelial growth factor in AIDS-related primary effusion lymphomas.

Authors:  Y Aoki; G Tosato; Y Nambu; A Iwamoto; R Yarchoan
Journal:  Blood       Date:  2000-02-01       Impact factor: 22.113

2.  IL-6 receptor independent stimulation of human gp130 by viral IL-6.

Authors:  J Müllberg; T Geib; T Jostock; S H Hoischen; P Vollmer; N Voltz; D Heinz; P R Galle; M Klouche; S Rose-John
Journal:  J Immunol       Date:  2000-05-01       Impact factor: 5.422

Review 3.  The epidemiology of acquired immunodeficiency syndrome malignancies.

Authors:  J J Goedert
Journal:  Semin Oncol       Date:  2000-08       Impact factor: 4.929

4.  Role of vascular endothelial growth factor/vascular permeability factor in the pathogenesis of Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphomas.

Authors:  Y Aoki; G Tosato
Journal:  Blood       Date:  1999-12-15       Impact factor: 22.113

5.  The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flow.

Authors:  A Peled; V Grabovsky; L Habler; J Sandbank; F Arenzana-Seisdedos; I Petit; H Ben-Hur; T Lapidot; R Alon
Journal:  J Clin Invest       Date:  1999-11       Impact factor: 14.808

6.  High levels of human herpesvirus 8 viral load, human interleukin-6, interleukin-10, and C reactive protein correlate with exacerbation of multicentric castleman disease in HIV-infected patients.

Authors:  E Oksenhendler; G Carcelain; Y Aoki; E Boulanger; A Maillard; J P Clauvel; F Agbalika
Journal:  Blood       Date:  2000-09-15       Impact factor: 22.113

7.  Viral and cellular cytokines in AIDS-related malignant lymphomatous effusions.

Authors:  Y Aoki; R Yarchoan; J Braun; A Iwamoto; G Tosato
Journal:  Blood       Date:  2000-08-15       Impact factor: 22.113

8.  Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling.

Authors:  Sang-Hoon Sin; Debasmita Roy; Ling Wang; Michelle R Staudt; Farnaz D Fakhari; Dhavalkumar D Patel; David Henry; William J Harrington; Blossom A Damania; Dirk P Dittmer
Journal:  Blood       Date:  2006-11-02       Impact factor: 22.113

9.  Estimation of human herpesvirus 8 prevalence in high-risk patients by analysis of humoral and cellular immunity.

Authors:  Brigitta M Lönard; Martina Sester; Urban Sester; Hans W Pees; Nikolaus Mueller-Lantzsch; Hans Köhler; Barbara C Gärtner
Journal:  Transplantation       Date:  2007-07-15       Impact factor: 4.939

10.  Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6 and G-protein-coupled receptor regulate angiopoietin-2 expression in lymphatic endothelial cells.

Authors:  Richard J Vart; Leonid L Nikitenko; Dimitrios Lagos; Matthew W B Trotter; Mark Cannon; Dimitra Bourboulia; Fiona Gratrix; Yasuhiro Takeuchi; Chris Boshoff
Journal:  Cancer Res       Date:  2007-05-01       Impact factor: 12.701
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  21 in total

1.  High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy.

Authors:  Thomas S Uldrick; Mark N Polizzotto; Karen Aleman; Deirdre O'Mahony; Kathleen M Wyvill; Victoria Wang; Vickie Marshall; Stefania Pittaluga; Seth M Steinberg; Giovanna Tosato; Denise Whitby; Richard F Little; Robert Yarchoan
Journal:  Blood       Date:  2011-04-12       Impact factor: 22.113

2.  IL-10 promoter transactivation by the viral K-RTA protein involves the host-cell transcription factors, specificity proteins 1 and 3.

Authors:  Masanori Miyazawa; Kohji Noguchi; Mana Kujirai; Kazuhiro Katayama; Satoshi Yamagoe; Yoshikazu Sugimoto
Journal:  J Biol Chem       Date:  2017-11-28       Impact factor: 5.157

3.  Kaposi sarcoma-associated herpesvirus (KSHV) induces a functional tumor-associated phenotype for oral fibroblasts.

Authors:  Lu Dai; Zhiqiang Qin; Michael Defee; Bryan P Toole; Keith L Kirkwood; Chris Parsons
Journal:  Cancer Lett       Date:  2011-12-17       Impact factor: 8.679

4.  Human herpesvirus 8 viral interleukin-6 interacts with splice variant 2 of vitamin K epoxide reductase complex subunit 1.

Authors:  Daming Chen; Emily Cousins; Gordon Sandford; John Nicholas
Journal:  J Virol       Date:  2011-11-30       Impact factor: 5.103

5.  Rituximab plus liposomal doxorubicin in HIV-infected patients with KSHV-associated multicentric Castleman disease.

Authors:  Thomas S Uldrick; Mark N Polizzotto; Karen Aleman; Kathleen M Wyvill; Vickie Marshall; Denise Whitby; Victoria Wang; Stefania Pittaluga; Deirdre O'Mahony; Seth M Steinberg; Richard F Little; Robert Yarchoan
Journal:  Blood       Date:  2014-10-20       Impact factor: 22.113

6.  HACE1, an E3 Ubiquitin Protein Ligase, Mitigates Kaposi's Sarcoma-Associated Herpesvirus Infection-Induced Oxidative Stress by Promoting Nrf2 Activity.

Authors:  Binod Kumar; Arunava Roy; Kumari Asha; Neelam Sharma-Walia; Mairaj Ahmed Ansari; Bala Chandran
Journal:  J Virol       Date:  2019-04-17       Impact factor: 5.103

7.  KSHV infects a subset of human tonsillar B cells, driving proliferation and plasmablast differentiation.

Authors:  Lynn M Hassman; Thomas J Ellison; Dean H Kedes
Journal:  J Clin Invest       Date:  2011-01-18       Impact factor: 14.808

8.  Kaposi's sarcoma-associated herpesvirus latency in endothelial and B cells activates gamma interferon-inducible protein 16-mediated inflammasomes.

Authors:  Vivek Vikram Singh; Nagaraj Kerur; Virginie Bottero; Sujoy Dutta; Sayan Chakraborty; Mairaj Ahmed Ansari; Nitika Paudel; Leela Chikoti; Bala Chandran
Journal:  J Virol       Date:  2013-02-06       Impact factor: 5.103

9.  Cellular corepressor TLE2 inhibits replication-and-transcription- activator-mediated transactivation and lytic reactivation of Kaposi's sarcoma-associated herpesvirus.

Authors:  Zhiheng He; Yunhua Liu; Deguang Liang; Zhuo Wang; Erle S Robertson; Ke Lan
Journal:  J Virol       Date:  2009-11-25       Impact factor: 5.103

10.  An MHV-68 Mutator Phenotype Mutant Virus, Confirmed by CRISPR/Cas9-Mediated Gene Editing of the Viral DNA Polymerase Gene, Shows Reduced Viral Fitness.

Authors:  Erika Trompet; Arturo Temblador; Sarah Gillemot; Dimitrios Topalis; Robert Snoeck; Graciela Andrei
Journal:  Viruses       Date:  2021-05-26       Impact factor: 5.048
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