| Literature DB >> 18319068 |
Seong-Cheol Park1, Bang Phuong Pham, Le Van Duyet, Baolei Jia, Sangmin Lee, Rui Yu, Sang Woo Han, Jae-Kyung Yang, Kyung-Soo Hahm, Gang-Won Cheong.
Abstract
Osmotically inducible protein C (OsmC) is involved in the cellular defense mechanism against oxidative stress caused by exposure to hyperoxides or elevated osmolarity. OsmC was identified by two-dimensional electrophoresis (2DE) analysis as a protein that is overexpressed in response to osmotic stress, but not under heat and oxidative stress. Here, an OsmC gene from T. kodakaraensis KOD1 was cloned and expressed in Escherichia coli. TkOsmC showed a homotetrameric structure based on gel filtration and electron microscopic analyses. TkOsmC has a significant peroxidase activity toward both organic and inorganic peroxides in high, but not in low temperature.Entities:
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Year: 2008 PMID： 18319068 DOI： 10.1016/j.bbapap.2008.02.002
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002