Literature DB >> 18318278

Microfluidics at the crossroad with point-of-care diagnostics.

Vincent Linder1.   

Abstract

Microfluidic devices have been long advertised as a key candidate to revolutionize point-of-care (POC) diagnostics. Recent advances in this field have addressed some of the most important issues, which limited the deployment of microfluidic devices outside of clinical laboratories. This contribution discusses important technical and economic constraints that microfluidic products must overcome to be adopted by healthcare systems. Two sets of technologies are described which comply with the constraints of the POC environment. As such, these technologies illustrate a possible route for the development of microfluidic devices, which could fulfil the needs of clinicians for disease staging and monitoring.

Mesh:

Year:  2007        PMID: 18318278     DOI: 10.1039/b706347d

Source DB:  PubMed          Journal:  Analyst        ISSN: 0003-2654            Impact factor:   4.616


  15 in total

1.  Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood.

Authors:  Daniel Y Joh; Angus M Hucknall; Qingshan Wei; Kelly A Mason; Margaret L Lund; Cassio M Fontes; Ryan T Hill; Rebecca Blair; Zackary Zimmers; Rohan K Achar; Derek Tseng; Raluca Gordan; Michael Freemark; Aydogan Ozcan; Ashutosh Chilkoti
Journal:  Proc Natl Acad Sci U S A       Date:  2017-08-07       Impact factor: 11.205

2.  High-throughput particle manipulation by hydrodynamic, electrokinetic, and dielectrophoretic effects in an integrated microfluidic chip.

Authors:  Shunbo Li; Ming Li; Kristelle Bougot-Robin; Wenbin Cao; Irene Yeung Yeung Chau; Weihua Li; Weijia Wen
Journal:  Biomicrofluidics       Date:  2013-03-20       Impact factor: 2.800

3.  Rise of the micromachines: microfluidics and the future of cytometry.

Authors:  Donald Wlodkowic; Zbigniew Darzynkiewicz
Journal:  Methods Cell Biol       Date:  2011       Impact factor: 1.441

4.  Transferring vertically aligned carbon nanotubes onto a polymeric substrate using a hot embossing technique for microfluidic applications.

Authors:  A Mathur; S S Roy; J A McLaughlin
Journal:  J R Soc Interface       Date:  2010-02-10       Impact factor: 4.118

5.  Highly sensitive and reusable Pt-black microfluidic electrodes for long-term electrochemical sensing.

Authors:  Liangliang Qiang; Santhisagar Vaddiraju; James F Rusling; Fotios Papadimitrakopoulos
Journal:  Biosens Bioelectron       Date:  2010-07-23       Impact factor: 10.618

6.  Challenges for rapid molecular HIV diagnostics.

Authors:  Marco L Schito; M Patricia D'Souza; S Michele Owen; Michael P Busch
Journal:  J Infect Dis       Date:  2010-04-15       Impact factor: 5.226

7.  Micro-bioreactor arrays for controlling cellular environments: design principles for human embryonic stem cell applications.

Authors:  Elisa Cimetta; Elisa Figallo; Christopher Cannizzaro; Nicola Elvassore; Gordana Vunjak-Novakovic
Journal:  Methods       Date:  2008-10-24       Impact factor: 3.608

Review 8.  Perspective on optical biosensors and integrated sensor systems.

Authors:  Frances S Ligler
Journal:  Anal Chem       Date:  2009-01-15       Impact factor: 6.986

Review 9.  Optical imaging techniques for point-of-care diagnostics.

Authors:  Hongying Zhu; Serhan O Isikman; Onur Mudanyali; Alon Greenbaum; Aydogan Ozcan
Journal:  Lab Chip       Date:  2012-10-09       Impact factor: 6.799

Review 10.  Point-of-Care Diagnostics: Recent Developments in a Connected Age.

Authors:  Samiksha Nayak; Nicole R Blumenfeld; Tassaneewan Laksanasopin; Samuel K Sia
Journal:  Anal Chem       Date:  2016-12-13       Impact factor: 6.986

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