Literature DB >> 18317973

The role of postoperative adjuvant chemotherapy following curative resection for gastric cancer: a meta-analysis.

Shu-Liang Zhao1, Jing-Yuan Fang.   

Abstract

To evaluate the effect of adjuvant chemotherapy on survival rates after curative resection of gastric cancer, MEDLINE (1969-2006), EMBASE (1974-2006), bibliographies, and review articles were searched for relevant articles. The meta-analysis was finally based on 15 trials that included 3212 patients. RR for death in the treated group was 0.90 (95% CI, 0.84-0.96) (P = 0.0010). Little or no significant benefits were suggested in subgroup analyses between different population and regimens either. Postoperative adjuvant chemotherapy for gastric cancer confers slightly significant benefits compared to the surgery only group. The prognoses after surgery may differ among various population groups or because of different regimens.

Entities:  

Mesh：

Year:  2008        PMID： 18317973     DOI： 10.1080/07357900701834686

Source DB:  PubMed          Journal:  Cancer Invest        ISSN： 0735-7907            Impact factor:   2.176


  16 in total

1.  Adjuvant FOLFOX-4 in patients with radically resected gastric cancer: Tolerability and prognostic factors.

Authors:  Chiara Carlomagno; Elide Matano; Roberto Bianco; Carolina Cimminiello; Antonella Prudente; Clorindo Pagliarulo; Anna Crispo; Lucia Cannella; Alfonso DE Stefano; Francesco Paolo D'Armiento; Sabino DE Placido
Journal:  Exp Ther Med       Date:  2010-07-01       Impact factor: 2.447

Review 2.  Adjuvant chemotherapy for gastric cancer: current evidence and future challenges.

Authors:  Rosalba Miceli; Gianluca Tomasello; Giacomo Bregni; Maria Di Bartolomeo; Filippo Pietrantonio
Journal:  World J Gastroenterol       Date:  2014-04-28       Impact factor: 5.742

3.  Postoperative chemoradiotherapy in gastric cancer: a phase I study of radiotherapy with dose escalation of oxaliplatin, 5-fluorouracil, and leucovorin (FOLFOX regimen).

Authors:  Xin Wang; Yongsheng Wang; Meng Qiu; Qiu Li; Zhi-ping Li; Bing He; Feng Xu; Ya-li Shen; Hong-feng Gou; Yu Yang; Dan Cao; Cheng Yi; Ji-yan Liu; De-yun Luo; Zheng-yin Liao; Feng Bi
Journal:  Med Oncol       Date:  2010-11-30       Impact factor: 3.064

Review 4.  Neoadjuvant or adjuvant therapy for resectable gastric cancer: a systematic review and practice guideline for North America.

Authors:  Greg Knight; Craig C Earle; Roxanne Cosby; Natalie Coburn; Youssef Youssef; Richard Malthaner; Rebecca K S Wong
Journal:  Gastric Cancer       Date:  2012-03-31       Impact factor: 7.370

5.  R0 resection in the treatment of gastric cancer: room for improvement.

Authors:  Alberto Biondi; Roberto Persiani; Ferdinando Cananzi; Marco Zoccali; Vincenzo Vigorita; Andrea Tufo; Domenico D'Ugo
Journal:  World J Gastroenterol       Date:  2010-07-21       Impact factor: 5.742

Review 6.  Treatment of gastric cancer.

Authors:  Michele Orditura; Gennaro Galizia; Vincenzo Sforza; Valentina Gambardella; Alessio Fabozzi; Maria Maddalena Laterza; Francesca Andreozzi; Jole Ventriglia; Beatrice Savastano; Andrea Mabilia; Eva Lieto; Fortunato Ciardiello; Ferdinando De Vita
Journal:  World J Gastroenterol       Date:  2014-02-21       Impact factor: 5.742

Review 7.  Chemotherapy for patients with gastric cancer after complete resection: a network meta-analysis.

Authors:  Ya-Wu Zhang; Yu-Long Zhang; Hui Pan; Feng-Xian Wei; You-Cheng Zhang; Yuan Shao; Wei Han; Hai-Peng Liu; Zhe-Yuan Wang; Sun-Hu Yang
Journal:  World J Gastroenterol       Date:  2014-01-14       Impact factor: 5.742

8.  The effect of adjuvant chemotherapy on stage IV (T4N1-3M0 and T1-3N3M0) gastric cancer.

Authors:  Tae Kyung Ha; Min Sung Jung; Kang Hong Lee; Kyeong Geun Lee; Sung Joon Kwon
Journal:  Cancer Res Treat       Date:  2009-03-31       Impact factor: 4.679

Review 9.  Roles of Nrf2 in Gastric Cancer: Targeting for Therapeutic Strategies.

Authors:  Tahereh Farkhondeh; Ali Mohammad Pourbagher-Shahri; Mohsen Azimi-Nezhad; Fatemeh Forouzanfar; Aranka Brockmueller; Milad Ashrafizadeh; Marjan Talebi; Mehdi Shakibaei; Saeed Samarghandian
Journal:  Molecules       Date:  2021-05-25       Impact factor: 4.411

10.  Adjuvant chemotherapy for elderly patients with gastric cancer after D2 gastrectomy.

Authors:  Ying Jin; Miao-zhen Qiu; De-shen Wang; Dong-sheng Zhang; Chao Ren; Long Bai; Hui-yan Luo; Zhi-qiang Wang; Feng-hua Wang; Yu-hong Li; Rui-hua Xu
Journal:  PLoS One       Date:  2013-01-24       Impact factor: 3.240
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