PURPOSE: To report the etiology, culture results, management techniques, and visual outcomes for pediatric endophthalmitis at Emory University for the past 10 years. METHODS: Retrospective chart review based on a computer generated database of all cases of endophthalmitis occurring in patients younger than 18 years from 1995 to 2005. RESULTS: Sixteen cases of pediatric endophthalmitis were identified. Ocular trauma and previous ocular surgery were the most common etiologies, accounting for 44% and 38% of cases respectively. Nine cases (56%) had positive vitreous cultures. Sixty-six percent of cases with positive vitreous cultures involved Gram-positive species. All patients were treated with intravitreal antibiotics. Primary vitrectomy was performed in nine cases. Subsequent to the intraocular infection, 6 eyes (38%) developed retinal detachments. At last follow-up, visual acuity of 20/400 or better was obtained in only 6 eyes (38%). CONCLUSIONS: Pediatric endophthalmitis in this series most commonly resulted from penetrating ocular trauma or from ocular surgery. Retinal detachment commonly occurred as a complication. Despite aggressive management with antibiotics and in many cases vitrectomy, visual outcomes were poor in this series.
PURPOSE: To report the etiology, culture results, management techniques, and visual outcomes for pediatric endophthalmitis at Emory University for the past 10 years. METHODS: Retrospective chart review based on a computer generated database of all cases of endophthalmitis occurring in patients younger than 18 years from 1995 to 2005. RESULTS: Sixteen cases of pediatric endophthalmitis were identified. Ocular trauma and previous ocular surgery were the most common etiologies, accounting for 44% and 38% of cases respectively. Nine cases (56%) had positive vitreous cultures. Sixty-six percent of cases with positive vitreous cultures involved Gram-positive species. All patients were treated with intravitreal antibiotics. Primary vitrectomy was performed in nine cases. Subsequent to the intraocular infection, 6 eyes (38%) developed retinal detachments. At last follow-up, visual acuity of 20/400 or better was obtained in only 6 eyes (38%). CONCLUSIONS:Pediatric endophthalmitis in this series most commonly resulted from penetrating ocular trauma or from ocular surgery. Retinal detachment commonly occurred as a complication. Despite aggressive management with antibiotics and in many cases vitrectomy, visual outcomes were poor in this series.
Authors: Hassan A Aziz; Audina M Berrocal; Robert A Sisk; Kristin Hartley; Magaly Diaz-Barbosa; Rose A Johnson; Ditte Hess; Sander R Dubovy; Timothy G Murray; Harry W Flynn Journal: Clin Ophthalmol Date: 2012-05-14