Literature DB >> 1831670

Myoclonic epileptic seizures during clozapine treatment: a report of three cases.

E Gouzoulis1, H Grunze, U von Bardeleben.   

Abstract

Three adult schizophrenic patients without a previous history of epilepsy are reported who, during clozapine treatment, developed paroxysmal EEG patterns and generalized myoclonic jerks without alteration of consciousness. These seizures were phenomenologically identical to those occurring in juvenile myoclonic epilepsy and were classified as generalized epileptic seizures. We tentatively conclude that generalized myoclonic epileptic seizures may be induced by clozapine.

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Year:  1991        PMID： 1831670     DOI： 10.1007/bf02279769

Source DB:  PubMed          Journal:  Eur Arch Psychiatry Clin Neurosci        ISSN： 0940-1334            Impact factor:   5.270


  11 in total

1.  Efficacy and adverse effects of clozapine in the treatment of schizophrenia and tardive dyskinesia--a retrospective study of 387 patients.

Authors:  D Naber; M Leppig; R Grohmann; H Hippius
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

2.  Side effects of clozapine.

Authors:  H J Gaertner; E Fischer; J Hoss
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

3.  [The incidence of abnormal EEG patterns with clozapine therapy (author's transl)].

Authors:  R Spatz; E Lorenzi; J Kugler; E Rüther
Journal:  Arzneimittelforschung       Date:  1978

4.  Paroxysmal EEG activity and psychopathology during the treatment with clozapine.

Authors:  M Koukkou; J Angst; D Zimmer
Journal:  Pharmakopsychiatr Neuropsychopharmakol       Date:  1979-03

5.  Drug-induced paroxysmal EEG-activities.

Authors:  J Kugler; E Lorenzi; R Spatz; H Zimmermann
Journal:  Pharmakopsychiatr Neuropsychopharmakol       Date:  1979-03

6.  Adverse effects of clozapine.

Authors:  R Grohmann; E Rüther; N Sassim; L G Schmidt
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

7.  A prospective study of clozapine in treatment-resistant schizophrenic patients. I. Preliminary report.

Authors:  H Y Meltzer; B Bastani; K Y Kwon; L F Ramirez; S Burnett; J Sharpe
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

8.  Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine.

Authors:  J Kane; G Honigfeld; J Singer; H Meltzer
Journal:  Arch Gen Psychiatry       Date:  1988-09

9.  Proposal for revised clinical and electroencephalographic classification of epileptic seizures. From the Commission on Classification and Terminology of the International League Against Epilepsy.

Authors: 
Journal:  Epilepsia       Date:  1981-08       Impact factor: 5.864

10.  Tolerability and therapeutic effect of clozapine. A retrospective investigation of 216 patients treated with clozapine for up to 12 years.

Authors:  U Juul Povlsen; U Noring; R Fog; J Gerlach
Journal:  Acta Psychiatr Scand       Date:  1985-02       Impact factor: 6.392
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  2 in total

1.  Clozapine-related EEG changes and seizures: dose and plasma-level relationships.

Authors:  Seema Varma; Delia Bishara; Frank M C Besag; David Taylor
Journal:  Ther Adv Psychopharmacol       Date:  2011-04

Review 2.  Clozapine-induced myoclonus: a case report and review of the literature.

Authors:  Ian J Osborne; Ronan J McIvor
Journal:  Ther Adv Psychopharmacol       Date:  2015-12
  2 in total

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