Literature DB >> 18316194

Synthesis and anti-HIV1 biological activity of novel 5''-ATSAO compounds.

Cyrille Tomassi1, Albert Nguyen Van Nhien, José Marco-Contelles, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Denis Postel.   

Abstract

Aza TSAO-T derivatives bearing a substituted dihydroisothiazole dioxide ring with a phenyl group at 5'' position were prepared. Biological evaluation showed that phenyl group gives rise to a dramatical decrease of the inhibitory effect.

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Year:  2008        PMID: 18316194     DOI: 10.1016/j.bmc.2008.02.026

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  1 in total

1.  Gas chromatography-mass spectroscopy analysis of bioactive petalostigma extracts: Toxicity, antibacterial and antiviral activities.

Authors:  F R Kalt; I E Cock
Journal:  Pharmacogn Mag       Date:  2014-01       Impact factor: 1.085

  1 in total

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