Literature DB >> 18316023

Ghrelin gets its GOAT.

James Gardiner1, Steve Bloom.   

Abstract

Ghrelin, a powerful appetite-stimulating hormone secreted by the stomach, is modified by an octanyl side chain on its third amino acid, a serine, which is essential for its activity. A recent study (Yang et al., 2008) reports identification of the enzyme catalyzing the addition of this octanyl, GOAT.

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Year:  2008        PMID: 18316023     DOI: 10.1016/j.cmet.2008.02.009

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  7 in total

Review 1.  Role of ghrelin in the pathophysiology of eating disorders: implications for pharmacotherapy.

Authors:  Sebastian Cardona Cano; Myrte Merkestein; Karolina P Skibicka; Suzanne L Dickson; Roger A H Adan
Journal:  CNS Drugs       Date:  2012-04-01       Impact factor: 5.749

Review 2.  Therapeutic applications of ghrelin agonists in the treatment of gastroparesis.

Authors:  Andrea Shin; John M Wo
Journal:  Curr Gastroenterol Rep       Date:  2015-02

3.  Acylated and des acyl ghrelin in human portal and systemic circulations.

Authors:  S Goodyear; R P Arasaradnam; N Quraishi; M Mottershead; C U Nwokolo
Journal:  Mol Biol Rep       Date:  2010-02-27       Impact factor: 2.316

4.  Ghrelin in chronic kidney disease.

Authors:  Wai W Cheung; Robert H Mak
Journal:  Int J Pept       Date:  2010-03-17

Review 5.  Inter-organ communication and regulation of beta cell function.

Authors:  Mehboob A Hussain; Elina Akalestou; Woo-Jin Song
Journal:  Diabetologia       Date:  2016-01-20       Impact factor: 10.122

Review 6.  Actions and therapeutic pathways of ghrelin for gastrointestinal disorders.

Authors:  Michael Camilleri; Athanasios Papathanasopoulos; Suwebatu T Odunsi
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2009-06       Impact factor: 46.802

Review 7.  From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation.

Authors:  Ken Howick; Brendan T Griffin; John F Cryan; Harriët Schellekens
Journal:  Int J Mol Sci       Date:  2017-01-27       Impact factor: 5.923

  7 in total

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