Literature DB >> 18313905

A high-throughput approach towards a novel formulation of fenofibrate in omega-3 oil.

Pasut Ratanabanangkoon1, Hector Guzman, Orn Almarsson, Dina Berkovitz, Stephanie Tokarcyzk, Arthur B Straughn, Hongming Chen.   

Abstract

A novel lipid formulation containing fenofibrate in omega-3 oil was developed using a novel high-throughput screening platform. The optimized formulation combines the cardiovascular health benefits from omega-3 oil with the potent lipid-regulating effect of fenofibrate. When tested against the current marketed product Tricor in healthy human volunteers, the new formulation was shown to be equivalent to Tricor.

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Year:  2008        PMID: 18313905     DOI: 10.1016/j.ejps.2008.01.005

Source DB:  PubMed          Journal:  Eur J Pharm Sci        ISSN: 0928-0987            Impact factor:   4.384


  1 in total

1.  Development and validation of bioanalytical UHPLC-UV method for simultaneous analysis of unchanged fenofibrate and its metabolite fenofibric acid in rat plasma: Application to pharmacokinetics.

Authors:  Rayan G Alamri; Kazi Mohsin; Ajaz Ahmad; Mohammad Raish; Fars K Alanazi
Journal:  Saudi Pharm J       Date:  2016-05-26       Impact factor: 4.330

  1 in total

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