Literature DB >> 18312216

Support vector machine approach to separate control and breast cancer serum samples.

Thang V Pham1, Mark A van de Wiel, Connie R Jimenez.   

Abstract

The paper presents two analyzes of the MALDI-TOF mass spectrometry dataset. Both analyzes use the support vector machine as a tool to build a prediction model. The first analysis which is our contribution to the competition uses the given spectra data without further processing. In the second analysis, we employed an additional preprocessing step consisting of peak detection, peak alignment and feature selection based on statistical tests. The experimental results suggest that the preprocessing step with feature selection improves prediction accuracy.

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Year:  2008        PMID: 18312216     DOI: 10.2202/1544-6115.1355

Source DB:  PubMed          Journal:  Stat Appl Genet Mol Biol        ISSN: 1544-6115


  2 in total

1.  A critical assessment of feature selection methods for biomarker discovery in clinical proteomics.

Authors:  Christin Christin; Huub C J Hoefsloot; Age K Smilde; B Hoekman; Frank Suits; Rainer Bischoff; Peter Horvatovich
Journal:  Mol Cell Proteomics       Date:  2012-10-31       Impact factor: 5.911

2.  Ovarian cancer detection from metabolomic liquid chromatography/mass spectrometry data by support vector machines.

Authors:  Wei Guan; Manshui Zhou; Christina Y Hampton; Benedict B Benigno; L Deette Walker; Alexander Gray; John F McDonald; Facundo M Fernández
Journal:  BMC Bioinformatics       Date:  2009-08-22       Impact factor: 3.169

  2 in total

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