Literature DB >> 18312034

Classification trees distinguish suicide attempters in major psychiatric disorders: a model of clinical decision making.

J John Mann1, Steven P Ellis, Christine M Waternaux, Xinhua Liu, Maria A Oquendo, Kevin M Malone, Beth S Brodsky, Gretchen L Haas, Dianne Currier.   

Abstract

OBJECTIVE: Determining risk for a suicide attempt in psychiatric patients requires assessment of multiple risk factors and knowledge of their relative importance. Classification and regression tree (CART) analysis generates decision trees that select the variables that perform best in identifying the group of interest and model clinical decision making. Hypothetical decision trees to identify recent and remote suicide attempters, weighted to increase sensitivity, were generated for psychiatric patients using correlates of past suicidal behavior.
METHOD: Correlates of past suicide attempts were identified in 408 patients with mood, schizophrenia spectrum, or personality disorders (DSM-IV). Correlated variables were entered into recursive partitioning statistical models to generate equally weighted and unequally weighted hypothetical decision trees for distinguishing recent (</= 30 days prior to study) and remote (> 250 days prior to study) suicide attempters from nonattempters. The study was conducted from December 1989 to November 1998.
RESULTS: In equally weighted trees, a recent past suicide attempt was best predicted by current suicidal ideation (sensitivity = 56%, specificity = 91%, positive predictive value = 69%), and no adequate model was found for remote attempts. In unequally weighted models, recent attempters were identified by suicidal ideation and comorbid borderline personality disorder (sensitivity = 73%, specificity = 80%, positive predictive value = 58%). Remote attempters were identified by lifetime aggression and current subjective depression (sensitivity = 89%, specificity = 36%, positive predictive value = 44%).
CONCLUSION: Current suicidal ideation is the best indicator of a recent suicide attempt in psychiatric patients. Indicators of a remote attempt are aggressive traits and current depression. Weighted decision trees can improve sensitivity and miss fewer attempters but with a cost in specificity.

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Year:  2008        PMID: 18312034      PMCID: PMC3773877          DOI: 10.4088/jcp.v69n0104

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN: 0160-6689            Impact factor:   4.384


  45 in total

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2.  Time-related predictors of suicide in major affective disorder.

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Review 3.  Mental disorders and suicide prevention.

Authors:  J K Lönnqvist; M M Henriksson; E T Isometsä; M J Marttunen; M E Heikkinen; H M Aro; K I Kuoppasalmi
Journal:  Psychiatry Clin Neurosci       Date:  1995-05       Impact factor: 5.188

4.  Suicide ideation at its worst point: a predictor of eventual suicide in psychiatric outpatients.

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Journal:  Suicide Life Threat Behav       Date:  1999

5.  Suidical ideation in severe depression.

Authors:  L Brådvik; M Berglund
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2000       Impact factor: 5.270

6.  Suicidal behavior in patients with schizophrenia and other psychotic disorders.

Authors:  E D Radomsky; G L Haas; J J Mann; J A Sweeney
Journal:  Am J Psychiatry       Date:  1999-10       Impact factor: 18.112

7.  Prospective study of fluoxetine treatment and suicidal behavior in affectively ill subjects.

Authors:  A C Leon; M B Keller; M G Warshaw; T I Mueller; D A Solomon; W Coryell; J Endicott
Journal:  Am J Psychiatry       Date:  1999-02       Impact factor: 18.112

8.  Toward a clinical model of suicidal behavior in psychiatric patients.

Authors:  J J Mann; C Waternaux; G L Haas; K M Malone
Journal:  Am J Psychiatry       Date:  1999-02       Impact factor: 18.112

9.  Suicide among subjects with personality disorders.

Authors:  E T Isometsä; M M Henriksson; M E Heikkinen; H M Aro; M J Marttunen; K I Kuoppasalmi; J K Lönnqvist
Journal:  Am J Psychiatry       Date:  1996-05       Impact factor: 18.112

10.  Clinical assessment versus research methods in the assessment of suicidal behavior.

Authors:  K M Malone; K Szanto; E M Corbitt; J J Mann
Journal:  Am J Psychiatry       Date:  1995-11       Impact factor: 18.112

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  30 in total

1.  Does PTSD moderate the relationship between social support and suicide risk in Iraq and Afghanistan War Veterans seeking mental health treatment?

Authors:  Matthew Jakupcak; Steven Vannoy; Zac Imel; Jessica W Cook; Alan Fontana; Robert Rosenheck; Miles McFall
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2.  Temporal relationships between Gulf War deployment and subsequent psychological disorders in Royal Australian Navy Gulf War veterans.

Authors:  Dean P McKenzie; Mark Creamer; Helen L Kelsall; Andrew B Forbes; Jillian F Ikin; Malcolm R Sim; Alexander C McFarlane
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3.  Sleep Duration and Insomnia Symptoms as Risk Factors for Suicidal Ideation in a Nationally Representative Sample.

Authors:  Subhajit Chakravorty; H Y Katy Siu; Linden Lalley-Chareczko; Gregory K Brown; James C Findley; Michael L Perlis; Michael A Grandner
Journal:  Prim Care Companion CNS Disord       Date:  2015-12-31

4.  The Risk of Repetition of Attempted Suicide Among Iranian Women with Psychiatric Disorders as Quantified by the Suicide Behaviors Questionnaire.

Authors:  Jalal Shakeri; Vahid Farnia; Nasrin Abdoli; Mohammad R Akrami; Farid Arman; Hania Shakeri
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5.  Clinical Correlates of Planned and Unplanned Suicide Attempts.

Authors:  Sadia R Chaudhury; Tanya Singh; Ainsley Burke; Barbara Stanley; J John Mann; Michael Grunebaum; M Elizabeth Sublette; Maria A Oquendo
Journal:  J Nerv Ment Dis       Date:  2016-11       Impact factor: 2.254

Review 6.  Integration of PKPD relationships into benefit-risk analysis.

Authors:  Francesco Bellanti; Rob C van Wijk; Meindert Danhof; Oscar Della Pasqua
Journal:  Br J Clin Pharmacol       Date:  2015-07-29       Impact factor: 4.335

Review 7.  Ketamine for Treatment of Suicidal Ideation and Reduction of Risk for Suicidal Behavior.

Authors:  Faryal Mallick; Cheryl B McCullumsmith
Journal:  Curr Psychiatry Rep       Date:  2016-06       Impact factor: 5.285

8.  Cross-national analysis of the associations among mental disorders and suicidal behavior: findings from the WHO World Mental Health Surveys.

Authors:  Matthew K Nock; Irving Hwang; Nancy Sampson; Ronald C Kessler; Matthias Angermeyer; Annette Beautrais; Guilherme Borges; Evelyn Bromet; Ronny Bruffaerts; Giovanni de Girolamo; Ron de Graaf; Silvia Florescu; Oye Gureje; Josep Maria Haro; Chiyi Hu; Yueqin Huang; Elie G Karam; Norito Kawakami; Viviane Kovess; Daphna Levinson; Jose Posada-Villa; Rajesh Sagar; Toma Tomov; Maria Carmen Viana; David R Williams
Journal:  PLoS Med       Date:  2009-08-11       Impact factor: 11.069

9.  Modifiable risk factors predicting major depressive disorder at four year follow-up: a decision tree approach.

Authors:  Philip J Batterham; Helen Christensen; Andrew J Mackinnon
Journal:  BMC Psychiatry       Date:  2009-11-22       Impact factor: 3.630

10.  Stratification of the severity of critically ill patients with classification trees.

Authors:  Javier Trujillano; Mariona Badia; Luis Serviá; Jaume March; Angel Rodriguez-Pozo
Journal:  BMC Med Res Methodol       Date:  2009-12-09       Impact factor: 4.615

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