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Literature DB >> 1831181

Murine candidiasis: sex differences in the severity of tissue lesions are not associated with levels of serum C3 and C5.

R B Ashman¹, P H Kay, D M Lynch, J M Papadimitriou.

Abstract

Mice deficient in the fifth component of complement are known to be extremely susceptible to lethal challenge with Candida albicans. However, male mice, that have significantly higher concentrations of serum C5 than females, were markedly more susceptible to infection. This difference was observed in both susceptible (CBA/H) and resistant (BALB/c) mice. Levels of serum C3 likewise showed no correlation with susceptibility.

Entities: Disease Species

Mesh：

Substances：

Year: 1991 PMID： 1831181 DOI： 10.1038/icb.1991.2

Source DB: PubMed Journal: Immunol Cell Biol ISSN： 0818-9641 Impact factor: 5.126

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Cited

7 in total

1. Impact of sex and ozone exposure on the course of pneumonia in wild type and SP-A (-/-) mice.

Authors: Anatoly N Mikerov; Sanmei Hu; Faryal Durrani; Xiaozhuang Gan; Guirong Wang; Todd M Umstead; David S Phelps; Joanna Floros
Journal: Microb Pathog Date: 2012-01-20 Impact factor: 3.738

2. Seasonality of blood neopterin levels in the Old Order Amish.

Authors: Hira Mohyuddin; Polymnia Georgiou; Abhishek Wadhawan; Melanie L Daue; Lisa A Brenner; Claudia Gragnoli; Erika F H Saunders; Dietmar Fuchs; Christopher A Lowry; Teodor T Postolache
Journal: Pteridines Date: 2017-12-02 Impact factor: 0.581

3. Histopathologic evaluation of lung and extrapulmonary tissues show sex differences in Klebsiella pneumoniae - infected mice under different exposure conditions.

Authors: Anatoly N Mikerov; Timothy K Cooper; Guirong Wang; Sanmei Hu; Todd M Umstead; David S Phelps; Joanna Floros
Journal: Int J Physiol Pathophysiol Pharmacol Date: 2011-09-06

7. Survival of Surfactant Protein-A1 and SP-A2 Transgenic Mice After Klebsiella pneumoniae Infection, Exhibits Sex-, Gene-, and Variant Specific Differences; Treatment With Surfactant Protein Improves Survival.

Authors: Nithyananda Thorenoor; Todd M Umstead; Xuesheng Zhang; David S Phelps; Joanna Floros
Journal: Front Immunol Date: 2018-10-16 Impact factor: 7.561

7 in total

Murine candidiasis: sex differences in the severity of tissue lesions are not associated with levels of serum C3 and C5.

1. Impact of sex and ozone exposure on the course of pneumonia in wild type and SP-A (-/-) mice.

2. Seasonality of blood neopterin levels in the Old Order Amish.

3. Histopathologic evaluation of lung and extrapulmonary tissues show sex differences in Klebsiella pneumoniae - infected mice under different exposure conditions.

4. Gender is a major factor in determining the severity of mycoplasma respiratory disease in mice.

Review 5. Production and function of cytokines in natural and acquired immunity to Candida albicans infection.

6. Letter to editor.

7. Survival of Surfactant Protein-A1 and SP-A2 Transgenic Mice After Klebsiella pneumoniae Infection, Exhibits Sex-, Gene-, and Variant Specific Differences; Treatment With Surfactant Protein Improves Survival.