| Literature DB >> 183108 |
K B Hellman, C D Lytle, L E Bockstahler.
Abstract
Ultaviolet enhanced (Weigle) reactivation of UV-irradiated herpes simplex virus in UV-irradiated CV-1 monkey kidney cell monolayers was decreased by caffeine. X-ray enhanced reactivation of UV-irradiated virus in X-irradiated monolayers (X-ray reactivation) and UV- or X-ray-inactivated capacity of the cells to support unirradiated virus plaque formation were unaffected by caffeine. The results suggest that a caffeine-sensitive process is necessary for the expression of Weigle reactivation for herpes virus. Since cafeine did not significantly affect X-ray reactivation, different mechanisms may be responsible for the expression of Weigle reactivation and X-ray reactivation.Entities:
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Year: 1976 PMID： 183108 DOI： 10.1016/0027-5107(76)90234-7
Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433