Literature DB >> 18309427

An efficient enantioselective method for asymmetric Michael addition of nitroalkanes to alpha,beta-unsaturated aldehydes.

Yongcan Wang1, Pengfei Li, Xinmiao Liang, Tony Y Zhang, Jinxing Ye.   

Abstract

The addition of nitroalkanes to alpha,beta-unsaturated aldehydes under the catalysis of (S)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine and lithium acetate as additive afforded gamma-nitroaldehydes in good yield and up to 97% ee.

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Year:  2008        PMID： 18309427     DOI： 10.1039/b717000a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

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Review 2.  Asymmetric Michael Addition in Synthesis of β-Substituted GABA Derivatives.

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Journal:  Angew Chem Int Ed Engl       Date:  2018-08-23       Impact factor: 15.336

4.  Synthesis of novel 1,2,4-thiadiazinane 1,1-dioxides via three component SuFEx type reaction.

Authors:  Mzilikazi F Khumalo; Ekemini D Akpan; Praveen K Chinthakindi; Edikarlos M Brasil; Kamal K Rajbongshi; Maya M Makatini; Thavendran Govender; Hendrik G Kruger; Tricia Naicker; Per I Arvidsson
Journal:  RSC Adv       Date:  2018-11-07       Impact factor: 3.361

5.  Enantioselective organocatalytic Michael reactions using chiral (R,R)-1,2-diphenylethylenediamine-derived thioureas.

Authors:  Jae Ho Shim; Min Ji Lee; Min Ho Lee; Byeong-Seon Kim; Deok-Chan Ha
Journal:  RSC Adv       Date:  2020-08-27       Impact factor: 4.036

6.  Organocatalytic cascade aza-Michael/hemiacetal reaction between disubstituted hydrazines and α,β-unsaturated aldehydes: Highly diastereo- and enantioselective synthesis of pyrazolidine derivatives.

Authors:  Zhi-Cong Geng; Jian Chen; Ning Li; Xiao-Fei Huang; Yong Zhang; Ya-Wen Zhang; Xing-Wang Wang
Journal:  Beilstein J Org Chem       Date:  2012-10-09       Impact factor: 2.883

Review 7.  Asymmetric organocatalysis at the service of medicinal chemistry.

Authors:  Alfredo Ricci
Journal:  ISRN Org Chem       Date:  2014-03-11

8.  Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases.

Authors:  Jan-Ytzen van der Meer; Harshwardhan Poddar; Bert-Jan Baas; Yufeng Miao; Mehran Rahimi; Andreas Kunzendorf; Ronald van Merkerk; Pieter G Tepper; Edzard M Geertsema; Andy-Mark W H Thunnissen; Wim J Quax; Gerrit J Poelarends
Journal:  Nat Commun       Date:  2016-03-08       Impact factor: 14.919

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Authors:  Sándor B Ötvös; Patricia Llanes; Miquel A Pericàs; C Oliver Kappe
Journal:  Org Lett       Date:  2020-10-07       Impact factor: 6.005
  9 in total

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