Literature DB >> 18309315

Conquering sexually transmitted diseases.

Michael N Starnbach1, Nadia R Roan.   

Abstract

Sexually transmitted diseases (STDs) are a major public-health problem and also a significant financial burden on the economy. Past and ongoing attempts to create vaccines against sexually transmitted pathogens have met with varying success. This article highlights some of the public-health and social problems that are associated with STDs and the technical and ethical challenges in treating them, and raises several questions that need to be addressed if STDs are to be conquered.

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Mesh：

Year:  2008        PMID： 18309315     DOI： 10.1038/nri2272

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  22 in total

Review 1.  Antibiotic resistance in Chlamydiae.

Authors:  Kelsi M Sandoz; Daniel D Rockey
Journal:  Future Microbiol       Date:  2010-09       Impact factor: 3.165

2.  Potential protective effect of a G>A SNP in the 3'UTR of HLA-A for Chlamydia trachomatis symptomatology and severity of infection.

Authors:  Marleen E Jansen; Ivan Branković; Joke Spaargaren; Sander Ouburg; Servaas A Morré
Journal:  Pathog Dis       Date:  2015-12-09       Impact factor: 3.166

3.  T cell responses in the absence of IFN-gamma exacerbate uterine infection with Chlamydia trachomatis.

Authors:  David C Gondek; Nadia R Roan; Michael N Starnbach
Journal:  J Immunol       Date:  2009-06-26       Impact factor: 5.422

4.  The broad-spectrum antiviral compound ST-669 restricts chlamydial inclusion development and bacterial growth and localizes to host cell lipid droplets within treated cells.

Authors:  Kelsi M Sandoz; William G Valiant; Steven G Eriksen; Dennis E Hruby; Robert D Allen; Daniel D Rockey
Journal:  Antimicrob Agents Chemother       Date:  2014-04-28       Impact factor: 5.191

5.  Chlamydia muridarum T cell antigens and adjuvants that induce protective immunity in mice.

Authors:  Hong Yu; Karuna P Karunakaran; Xiaozhou Jiang; Caixia Shen; Peter Andersen; Robert C Brunham
Journal:  Infect Immun       Date:  2012-01-30       Impact factor: 3.441

6.  Chlamydia muridarum T-cell antigens formulated with the adjuvant DDA/TDB induce immunity against infection that correlates with a high frequency of gamma interferon (IFN-gamma)/tumor necrosis factor alpha and IFN-gamma/interleukin-17 double-positive CD4+ T cells.

Authors:  Hong Yu; Xiaozhou Jiang; Caixia Shen; Karuna P Karunakaran; Janina Jiang; Nicole L Rosin; Robert C Brunham
Journal:  Infect Immun       Date:  2010-03-15       Impact factor: 3.441

7.  Immunization with live and dead Chlamydia muridarum induces different levels of protective immunity in a murine genital tract model: correlation with MHC class II peptide presentation and multifunctional Th1 cells.

Authors:  Hong Yu; Karuna P Karunakaran; Isabelle Kelly; Caixia Shen; Xiaozhou Jiang; Leonard J Foster; Robert C Brunham
Journal:  J Immunol       Date:  2011-02-04       Impact factor: 5.422

Review 8.  Antiviral immune responses in the genital tract: clues for vaccines.

Authors:  Akiko Iwasaki
Journal:  Nat Rev Immunol       Date:  2010-09-10       Impact factor: 53.106

9.  Evaluation of a multisubunit recombinant polymorphic membrane protein and major outer membrane protein T cell vaccine against Chlamydia muridarum genital infection in three strains of mice.

Authors:  Hong Yu; Karuna P Karunakaran; Xiaozhou Jiang; Robert C Brunham
Journal:  Vaccine       Date:  2014-06-30       Impact factor: 3.641

10.  Novel Chlamydia muridarum T cell antigens induce protective immunity against lung and genital tract infection in murine models.

Authors:  Hong Yu; Xiaozhou Jiang; Caixia Shen; Karuna P Karunakaran; Robert C Brunham
Journal:  J Immunol       Date:  2009-02-01       Impact factor: 5.422
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