Literature DB >> 18308979

Sharing data and analytical resources securely in a biomedical research Grid environment.

Stephen Langella1, Shannon Hastings, Scott Oster, Tony Pan, Ashish Sharma, Justin Permar, David Ervin, B Barla Cambazoglu, Tahsin Kurc, Joel Saltz.   

Abstract

OBJECTIVES: To develop a security infrastructure to support controlled and secure access to data and analytical resources in a biomedical research Grid environment, while facilitating resource sharing among collaborators.
DESIGN: A Grid security infrastructure, called Grid Authentication and Authorization with Reliably Distributed Services (GAARDS), is developed as a key architecture component of the NCI-funded cancer Biomedical Informatics Grid (caBIG). The GAARDS is designed to support in a distributed environment 1) efficient provisioning and federation of user identities and credentials; 2) group-based access control support with which resource providers can enforce policies based on community accepted groups and local groups; and 3) management of a trust fabric so that policies can be enforced based on required levels of assurance. MEASUREMENTS: GAARDS is implemented as a suite of Grid services and administrative tools. It provides three core services: Dorian for management and federation of user identities, Grid Trust Service for maintaining and provisioning a federated trust fabric within the Grid environment, and Grid Grouper for enforcing authorization policies based on both local and Grid-level groups.
RESULTS: The GAARDS infrastructure is available as a stand-alone system and as a component of the caGrid infrastructure. More information about GAARDS can be accessed at http://www.cagrid.org.
CONCLUSIONS: GAARDS provides a comprehensive system to address the security challenges associated with environments in which resources may be located at different sites, requests to access the resources may cross institutional boundaries, and user credentials are created, managed, revoked dynamically in a de-centralized manner.

Entities:  

Mesh:

Year:  2008        PMID: 18308979      PMCID: PMC2409996          DOI: 10.1197/jamia.M2662

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  6 in total

1.  caCORE: a common infrastructure for cancer informatics.

Authors:  Peter A Covitz; Frank Hartel; Carl Schaefer; Sherri De Coronado; Gilberto Fragoso; Himanso Sahni; Scott Gustafson; Kenneth H Buetow
Journal:  Bioinformatics       Date:  2003-12-12       Impact factor: 6.937

Review 2.  Informatics in radiology: GridCAD: grid-based computer-aided detection system.

Authors:  Tony C Pan; Metin N Gurcan; Stephen A Langella; Scott W Oster; Shannon L Hastings; Ashish Sharma; Benjamin G Rutt; David W Ervin; Tahsin M Kurc; Khan M Siddiqui; Joel H Saltz; Eliot L Siegel
Journal:  Radiographics       Date:  2007 May-Jun       Impact factor: 5.333

3.  caGrid 1.0: a Grid enterprise architecture for cancer research.

Authors:  Scott Oster; Stephen Langella; Shannon Hastings; David Ervin; Ravi Madduri; Tahsin Kurc; Frank Siebenlist; Peter Covitz; Krishnakant Shanbhag; Ian Foster; Joel Saltz
Journal:  AMIA Annu Symp Proc       Date:  2007-10-11

4.  caGrid: design and implementation of the core architecture of the cancer biomedical informatics grid.

Authors:  Joel Saltz; Scott Oster; Shannon Hastings; Stephen Langella; Tahsin Kurc; William Sanchez; Manav Kher; Arumani Manisundaram; Krishnakant Shanbhag; Peter Covitz
Journal:  Bioinformatics       Date:  2006-06-09       Impact factor: 6.937

5.  The Cancer Biomedical Informatics Grid (caBIG) Security Infrastructure.

Authors:  Stephen Langella; Scott Oster; Shannon Hastings; Frank Siebenlist; Joshua Phillips; David Ervin; Justin Permar; Tahsin Kurc; Joel Saltz
Journal:  AMIA Annu Symp Proc       Date:  2007-10-11

6.  GridIMAGE: a novel use of grid computing to support interactive human and computer-assisted detection decision support.

Authors:  Metin N Gurcan; Tony Pan; Ashish Sharma; Tahsin Kurc; Scott Oster; Stephen Langella; Shannon Hastings; Khan M Siddiqui; Eliot L Siegel; Joel Saltz
Journal:  J Digit Imaging       Date:  2007-06       Impact factor: 4.056

  6 in total
  8 in total

1.  caTIES: a grid based system for coding and retrieval of surgical pathology reports and tissue specimens in support of translational research.

Authors:  Rebecca S Crowley; Melissa Castine; Kevin Mitchell; Girish Chavan; Tara McSherry; Michael Feldman
Journal:  J Am Med Inform Assoc       Date:  2010 May-Jun       Impact factor: 4.497

Review 2.  Identifiability in biobanks: models, measures, and mitigation strategies.

Authors:  Bradley Malin; Grigorios Loukides; Kathleen Benitez; Ellen Wright Clayton
Journal:  Hum Genet       Date:  2011-07-08       Impact factor: 4.132

3.  A caGRID-ENABLED, LEARNING BASED IMAGE SEGMENTATION METHOD FOR HISTOPATHOLOGY SPECIMENS.

Authors:  David J Foran; Lin Yang; Oncel Tuzel; Wenjin Chen; Jun Hu; Tahsin M Kurc; Renato Ferreira; Joel H Saltz
Journal:  Proc IEEE Int Symp Biomed Imaging       Date:  2009-07-01

4.  HPC AND GRID COMPUTING FOR INTEGRATIVE BIOMEDICAL RESEARCH.

Authors:  Tahsin Kurc; Shannon Hastings; Vijay Kumar; Stephen Langella; Ashish Sharma; Tony Pan; Scott Oster; David Ervin; Justin Permar; Sivaramakrishnan Narayanan; Yolanda Gil; Ewa Deelman; Mary Hall; Joel Saltz
Journal:  Int J High Perform Comput Appl       Date:  2009-08-01       Impact factor: 1.942

5.  CaGrid Workflow Toolkit: a Taverna based workflow tool for cancer grid.

Authors:  Wei Tan; Ravi Madduri; Alexandra Nenadic; Stian Soiland-Reyes; Dinanath Sulakhe; Ian Foster; Carole A Goble
Journal:  BMC Bioinformatics       Date:  2010-11-02       Impact factor: 3.169

6.  Adoption and Adaptation of caGrid for CTSA.

Authors:  Shannon Hastings; Scott Oster; Stephen Langella; Calixto Melean; Tara Borlawsky; Rakesh Dhavel; Philip Payne
Journal:  Summit Transl Bioinform       Date:  2009-03-01

7.  caGrid-Enabled caBIG Silver Level Compatible Head and Neck Cancer Tissue Database System.

Authors:  Haibin Wang; Erik Bouzyk; Anna Kuehn; Susan Muller; Zhengjia Chen; Fadlo R Khuri; Dong M Shin; André Rogatko; Mourad Tighiouart
Journal:  Open Med Inform J       Date:  2010-09-01

8.  Semantic web data warehousing for caGrid.

Authors:  Jamie P McCusker; Joshua A Phillips; Alejandra González Beltrán; Anthony Finkelstein; Michael Krauthammer
Journal:  BMC Bioinformatics       Date:  2009-10-01       Impact factor: 3.307

  8 in total

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