Literature DB >> 18308743

High-prevalence and high-estimated incidence of HIV infection among new injecting drug users in Estonia: need for large scale prevention programs.

Anneli Uusküla1, Mart Kals, Kristiina Rajaleid, Katri Abel, Ave Talu, Kristi Rüütel, Lucy Platt, Tim Rhodes, Jack Dehovitz, Don Des Jarlais.   

Abstract

OBJECTIVE: To examine HIV risk behavior and HIV infection among new injectors in Tallinn, Estonia. Design and methods Data from two cross-sectional surveys of injecting drug users (IDUs) recruited from a syringe exchange program (N = 162, Study 1) or using respondent driven sampling (N = 350, Study 2). Behavioral surveys were administered; serum samples were collected for HIV testing. Subjects were categorized into new injectors (injecting < or = 3 years) and long-term injectors (injecting > 3 years).
RESULTS: Twenty-eight of 161 (17%, Study 1) and 73/350 (21%, Study 2) of the study subjects were new injectors. HIV infection was substantial among the newer injectors: HIV prevalence was 50% (Study 1) and 34% (Study 2), and estimated HIV incidence 31/100 PY and 21/100 PY, respectively. In Study 2, new injectors were more likely to be female and ethnic Estonian and less likely to be injecting daily compared with long-term injectors. No significant difference was found among two groups on sharing injecting equipment or reported number of sexual partners.
CONCLUSIONS: A continuing HIV epidemic among new injectors is of critical public health concern. Interventions to prevent initiation into injecting drug use and scaling up HIV prevention programs for IDUs in Estonia are of utmost importance.

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Year:  2008        PMID: 18308743      PMCID: PMC2925676          DOI: 10.1093/pubmed/fdn014

Source DB:  PubMed          Journal:  J Public Health (Oxf)        ISSN: 1741-3842            Impact factor:   2.341


  30 in total

1.  A comparison of HIV risk behaviors between new and long-term injection drug users.

Authors:  D D Chitwood; M Comerford; K R Kitner; W Palacios; J Sanchez
Journal:  Subst Use Misuse       Date:  2001-01       Impact factor: 2.164

2.  HIV prevalence and risk behaviors among new initiates into injection drug use over the age of 40 years old.

Authors:  M Carneiro; C Fuller; M C Doherty; D Vlahov
Journal:  Drug Alcohol Depend       Date:  1999-03-01       Impact factor: 4.492

3.  Injecting equipment sharing among injecting drug users in Togliatti City, Russian Federation: maximizing the protective effects of syringe distribution.

Authors:  Tim Rhodes; Ali Judd; Larissa Mikhailova; Anya Sarang; Mikhail Khutorskoy; Lucy Platt; Catherine M Lowndes; Adrian Renton
Journal:  J Acquir Immune Defic Syndr       Date:  2004-03-01       Impact factor: 3.731

Review 4.  HIV epidemic in Estonia in the third decade of the AIDS era.

Authors:  Kristi Rüütel; Anneli Uusküla
Journal:  Scand J Infect Dis       Date:  2006

5.  Evaluation of 14 commercial HIV-1/HIV-2 antibody assays using serum panels of different geographical origin and clinical stage including a unique seroconversion panel.

Authors:  R Thorstensson; S Andersson; S Lindbäck; F Dias; F Mhalu; H Gaines; G Biberfeld
Journal:  J Virol Methods       Date:  1998-02       Impact factor: 2.014

6.  High hepatitis C incidence in new injecting drug users: a policy failure?

Authors:  Lisa Maher; Jiong Li; Bin Jalaludin; Kerry G Chant; John M Kaldor
Journal:  Aust N Z J Public Health       Date:  2007-02       Impact factor: 2.939

7.  The role of "long-term" and "new" injectors in a declining HIV/AIDS epidemic in Rio de Janeiro, Brazil.

Authors:  Mariana A Hacker; Samuel R Friedman; Paulo Roberto Telles; Sylvia Lopes Teixeira; Vera Bongertz; Mariza G Morgado; Francisco Inácio Bastos
Journal:  Subst Use Misuse       Date:  2005       Impact factor: 2.164

8.  Increasing ethnic differences in mortality in Estonia after the collapse of the Soviet Union.

Authors:  Mall Leinsalu; Denny Vågerö; Anton E Kunst
Journal:  J Epidemiol Community Health       Date:  2004-07       Impact factor: 3.710

9.  High prevalence of blood-borne virus infections and high-risk behaviour among injecting drug users in Tallinn, Estonia.

Authors:  Anneli Uusküla; Louise Anne McNutt; Jack Dehovitz; Krista Fischer; Robert Heimer
Journal:  Int J STD AIDS       Date:  2007-01       Impact factor: 1.359

10.  Modelling the force of infection for hepatitis B and hepatitis C in injecting drug users in England and Wales.

Authors:  A J Sutton; N J Gay; W J Edmunds; V D Hope; O N Gill; M Hickman
Journal:  BMC Infect Dis       Date:  2006-06-08       Impact factor: 3.090

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  22 in total

1.  Agent-based and phylogenetic analyses reveal how HIV-1 moves between risk groups: injecting drug users sustain the heterosexual epidemic in Latvia.

Authors:  Frederik Graw; Thomas Leitner; Ruy M Ribeiro
Journal:  Epidemics       Date:  2012-05-02       Impact factor: 4.396

2.  Estonia at the threshold of the fourth decade of the AIDS era in Europe.

Authors:  Kaja-Triin Laisaar; Radko Avi; Jack DeHovitz; Anneli Uusküla
Journal:  AIDS Res Hum Retroviruses       Date:  2011-01-11       Impact factor: 2.205

3.  Multiple routes of drug administration and HIV risk among injecting drug users.

Authors:  Sigrid Vorobjov; Anneli Uusküla; Don C Des Jarlais; Katri Abel-Ollo; Ave Talu; Kristi Rüütel
Journal:  J Subst Abuse Treat       Date:  2011-11-23

4.  A decline in the prevalence of injecting drug users in Estonia, 2005-2009.

Authors:  Anneli Uusküla; Kristiina Rajaleid; Ave Talu; Katri Abel-Ollo; Don C Des Jarlais
Journal:  Int J Drug Policy       Date:  2013-01-03

5.  Can HIV and Hepatitis C Virus Infection be Eliminated Among Persons Who Inject Drugs?

Authors:  David C Perlman; Don C Des Jarlais; Jonathan Feelemyer
Journal:  J Addict Dis       Date:  2015

6.  Homelessness and Other Risk Factors for HIV Infection in the Current Outbreak Among Injection Drug Users in Athens, Greece.

Authors:  Vana Sypsa; Dimitrios Paraskevis; Meni Malliori; Georgios K Nikolopoulos; Anastasios Panopoulos; Maria Kantzanou; Antigoni Katsoulidou; Mina Psichogiou; Anastasios Fotiou; Anastasia Pharris; Marita Van De Laar; Lucas Wiessing; Don Des Jarlais; Samuel R Friedman; Angelos Hatzakis
Journal:  Am J Public Health       Date:  2015-01       Impact factor: 9.308

7.  Combined prevention for persons who inject drugs in the HIV epidemic in a transitional country: the case of Tallinn, Estonia.

Authors:  Anneli Uusküla; Don C Des Jarlais; Mait Raag; Steven D Pinkerton; Jonathan Feelemyer
Journal:  AIDS Care       Date:  2014-07-23

Review 8.  HIV infection among persons who inject drugs: ending old epidemics and addressing new outbreaks.

Authors:  Don C Des Jarlais; Thomas Kerr; Patrizia Carrieri; Jonathan Feelemyer; Kamyar Arasteh
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9.  Comparison of injecting drug users who obtain syringes from pharmacies and syringe exchange programs in Tallinn, Estonia.

Authors:  Sigrid Vorobjov; Anneli Uusküla; Katri Abel-Ollo; Ave Talu; Kristi Rüütel; Don C Des Jarlais
Journal:  Harm Reduct J       Date:  2009-02-20

10.  Informed recruitment in partner studies of HIV transmission: an ethical issue in couples research.

Authors:  Louise-Anne McNutt; Elisa J Gordon; Anneli Uusküla
Journal:  BMC Med Ethics       Date:  2009-08-27       Impact factor: 2.652

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