S Hamouda1, C Karila, T Connault, P Scheinmann, J de Blic. 1. Université Paris Descartes, Assistance Publique des hôpitaux de Paris, Hôpital Necker Enfants Malades, Service de Pneumologie et d'Allergologie Pédiatriques, Paris, France.
Abstract
BACKGROUND: Allergic rhinitis (AR) and asthma frequently coexist but has rarely been evaluated in children. OBJECTIVE: This prospective study aimed to estimate the prevalence of AR in asthmatic children, and ascertain whether AR is a risk factor for the severity of asthma. METHODS: The questionnaire, modified from the adult form of the score for allergic rhinitis (SFAR), was completed by 404 asthmatic children aged 3-18 years seen in the outpatient clinic between June 2005 and July 2007. Each item was assigned a number of points with a final score ranging from 0 to 17. AR and asthma were classified according to ARIA and GINA 2004 recommendations, respectively. RESULTS: AR was diagnosed in 237 patients (58.7%). It was intermittent in 57.8% of the patients and persistent in 42.2%. A total score >or=9 was discriminant for AR (sensitivity=91.1%, specificity=95.2%, positive predictive value=96.4%, negative predictive value=88.3%, Youden's Index=0.86). The proportion of children having mild or moderate-to-severe asthma was independent of the presence of AR, 61.6% of moderate-to-severe asthmatic children and 55.4% of intermittent and mild asthmatic children having AR. CONCLUSION: AR and asthma are frequently associated (58.7%). The SFAR adapted for children seems to be a simple and a reliable tool to detect AR in asthmatic children.
BACKGROUND:Allergic rhinitis (AR) and asthma frequently coexist but has rarely been evaluated in children. OBJECTIVE: This prospective study aimed to estimate the prevalence of AR in asthmatic children, and ascertain whether AR is a risk factor for the severity of asthma. METHODS: The questionnaire, modified from the adult form of the score for allergic rhinitis (SFAR), was completed by 404 asthmatic children aged 3-18 years seen in the outpatient clinic between June 2005 and July 2007. Each item was assigned a number of points with a final score ranging from 0 to 17. AR and asthma were classified according to ARIA and GINA 2004 recommendations, respectively. RESULTS: AR was diagnosed in 237 patients (58.7%). It was intermittent in 57.8% of the patients and persistent in 42.2%. A total score >or=9 was discriminant for AR (sensitivity=91.1%, specificity=95.2%, positive predictive value=96.4%, negative predictive value=88.3%, Youden's Index=0.86). The proportion of children having mild or moderate-to-severe asthma was independent of the presence of AR, 61.6% of moderate-to-severe asthmatic children and 55.4% of intermittent and mild asthmatic children having AR. CONCLUSION: AR and asthma are frequently associated (58.7%). The SFAR adapted for children seems to be a simple and a reliable tool to detect AR in asthmatic children.
Authors: Brenda Carla Lima Araújo; Thales Rafael Correia de Melo Lima; Vanessa Tavares de Gois-Santos; Gerlane Karla Bezerra Oliveira Nascimento; Paulo Ricardo Martins-Filho; Silvia de Magalhães Simões Journal: Eur Arch Otorhinolaryngol Date: 2021-01-02 Impact factor: 2.503
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Authors: Ahmad R Sedaghat; Elizabeth C Matsui; Sachin N Baxi; Mary E Bollinger; Rachel Miller; Matthew Perzanowski; Wanda Phipatanakul Journal: J Allergy Clin Immunol Pract Date: 2015-10-02