| Literature DB >> 18307024 |
Kotaro Shibagaki1, Koichi Fujita, Shinji Nakayama, Mamoru Takenaka, Nobuhiko Fukuba, Saori Matsui, Masato Ozaka, Hiroshi Yoshinaga, Akira Masuzawa, Akihiko Watanabe, Hitoshi Fujiwara, Atsushi Sugawara, Tsuyoshi Fujita, Hidekazu Mukai, Yoshikazu Kinoshita.
Abstract
A 51-year-old woman with an unresectable pancreatic tumor that was histologically diagnosed as an adenosquamous carcinoma underwent chemoradiotherapy with 5-fluourouracil (FU) and low-dose cisplatin (low-dose FP). Because we recognized a partial response to the chemoradiotherapy, we subsequently administered combined chemotherapy with S-1 and cisplatin. After one course of this combined chemotherapy, the tumor was further reduced in size and became difficult to discern on abdominal computed tomography (CT). We have continued to administer the S-1 and cisplatin combined chemotherapy, and the patient is still alive. After 20 months of treatment, the tumor has not recurred (as assessed by abdominal CT). Additionally, we have not seen elevation of tumor markers. This report presents the successful use of chemoradiotherapy with low-dose FP and additional combined chemotherapy with S-1 and cisplatin for unresectable pancreatic adenosquamous carcinoma.Entities:
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Year: 2008 PMID： 18307024 DOI： 10.1007/s10147-007-0690-x
Source DB: PubMed Journal: Int J Clin Oncol ISSN： 1341-9625 Impact factor: 3.402