PURPOSE: To study the effects of smoking on the postoperative outcome of lung cancer surgery. METHODS: The subjects were 571 patients who underwent surgery for primary lung cancer. The patients were divided into the following groups according to their smoking history: a nonsmoker group (n = 218), a former smoker group (n = 140), and a current smoker group (n = 213). RESULTS: The 5-year survival rates were 56.2%, 40.9%, and 34.0% in the nonsmoker, former smoker, and current smoker groups, respectively. These differences were significant. According to a multivariable analysis, smoking was a significant factor affecting the postoperative prognosis of patients undergoing surgery for lung cancer. In analyzing the causes of death, there were more deaths caused by other diseases such as multiple organ cancer, respiratory disorder, cardiovascular disease, and surgery-related events in the former smoker and current smoker groups than in the nonsmoker group. CONCLUSIONS: Smoking was significantly predictive of a poor prognosis after lung cancer surgery.
PURPOSE: To study the effects of smoking on the postoperative outcome of lung cancer surgery. METHODS: The subjects were 571 patients who underwent surgery for primary lung cancer. The patients were divided into the following groups according to their smoking history: a nonsmoker group (n = 218), a former smoker group (n = 140), and a current smoker group (n = 213). RESULTS: The 5-year survival rates were 56.2%, 40.9%, and 34.0% in the nonsmoker, former smoker, and current smoker groups, respectively. These differences were significant. According to a multivariable analysis, smoking was a significant factor affecting the postoperative prognosis of patients undergoing surgery for lung cancer. In analyzing the causes of death, there were more deaths caused by other diseases such as multiple organ cancer, respiratory disorder, cardiovascular disease, and surgery-related events in the former smoker and current smoker groups than in the nonsmoker group. CONCLUSIONS: Smoking was significantly predictive of a poor prognosis after lung cancer surgery.
Authors: T Fujisawa; T Iizasa; Y Saitoh; Y Sekine; S Motohashi; T Yasukawa; K Shibuya; K Hiroshima; H Ohwada Journal: J Clin Oncol Date: 1999-07 Impact factor: 44.544
Authors: Robert A Meguid; Craig M Hooker; James Harris; Li Xu; William H Westra; J Timothy Sherwood; Marc Sussman; Stephen M Cattaneo; James Shin; Solange Cox; Joani Christensen; Yelena Prints; Nance Yuan; Jennifer Zhang; Stephen C Yang; Malcolm V Brock Journal: Chest Date: 2010-05-27 Impact factor: 9.410
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Authors: Mike R Sung; Pascale Tomasini; Lisa W Le; Suzanne Kamel-Reid; Ming-Sound Tsao; Geoffrey Liu; Penelope A Bradbury; Frances A Shepherd; Janice J N Li; Ronald Feld; Natasha B Leighl Journal: JTO Clin Res Rep Date: 2021-12-04